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Details on Person An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
| Class:Id | LiteratureReference:1181011 |
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| _displayName | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor |
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| _timestamp | 2011-01-26 20:05:45 |
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| author | [Person:1181023] Zhang, X
[Person:1181010] Gureasko, J
[Person:1181015] Shen, K
[Person:1112720] Cole, PA
[Person:187751] Kuriyan, J |
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| created | [InstanceEdit:1181016] Orlic-Milacic, Marija, 2011-01-26 |
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| journal | Cell |
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| pages | 1137-49 |
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| pubMedIdentifier | 16777603 |
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| title | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor |
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| volume | 125 |
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| year | 2006 |
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| (literatureReference) | [Reaction:1169421] Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers [Homo sapiens]
[Pathway:1169434] Signaling by constitutively active EGFR kinase domain mutants [Homo sapiens]
[Reaction:1220613] EGF-induced dimerization of ligand-responsive EGFR mutants [Homo sapiens]
[Reaction:1220614] Spontaneous dimerization of ligand-responsive EGFR mutants [Homo sapiens]
[Summation:1173215] EGFR ligand-responsive mutants dimerize spontaneously, witho...
[Summation:1181055] L861Q, a substitution of leucine 861 with glutamine, is a do...
[Summation:1181246] Signaling by EGFR is frequently activated in cancer through ...
[EntityWithAccessionedSequence:1177542] EGFR L861Q [plasma membrane] [Homo sapiens] |
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