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Details on Person Gefitinib [cytosol]
| Class:Id | ChemicalDrug:1169429 |
| _displayName | Gefitinib [cytosol] |
| _timestamp | 2018-12-12 00:29:42 |
| compartment | [Compartment:70101] cytosol |
| created | [InstanceEdit:1169430] Orlic-Milacic, Marija, 2011-01-18 |
| crossReference | [DatabaseIdentifier:9628106] ChEBI:49668 |
| disease | [Disease:1500689] cancer |
| literatureReference | [LiteratureReference:1181162] ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy [LiteratureReference:1169414] Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity |
| modified | [InstanceEdit:1169436] Orlic-Milacic, Marija, 2011-01-18 [InstanceEdit:1181158] Orlic-Milacic, Marija, 2011-01-28 [InstanceEdit:1181170] Orlic-Milacic, Marija, 2011-01-28 [InstanceEdit:1217487] Orlic-Milacic, Marija, 2011-02-16 [InstanceEdit:1220594] Orlic-Milacic, Marija, 2011-02-22 [InstanceEdit:1667319] Orlic-Milacic, Marija, 2011-10-14 [InstanceEdit:9016686] Orlic-Milacic, Marija, 2017-08-14 [InstanceEdit:9028147] Weiser, JD [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619953] Wu, G, 2018-09-19 [InstanceEdit:9627975] Wu, G, 2018-11-05 [InstanceEdit:9631716] Wu, G, 2018-12-12 |
| name | Gefitinib Iressa ZD1839 Reversible tyrosine kinase inhibitor gefitinib EGFR specific |
| referenceEntity | [ReferenceTherapeutic:9016663] gefitinib [Guide to Pharmacology:4941] |
| stableIdentifier | [StableIdentifier:2018474] R-ALL-1169429.2 |
| summation | [Summation:1181169] Gefitinib (ZD1839, Iressa) is a low-molecular-weight EGFR ty... |
| (hasComponent) | [Complex:1169431] EGFR G719S mutant:gefitinib [plasma membrane] [Homo sapiens] [Complex:9665139] ERBB2 L755_T759del:gefitinib [plasma membrane] [Homo sapiens] |
| (hasMember) | [DefinedSet:1176053] Reversible EGFR-specific TKIs [cytosol] [DefinedSet:9663690] neratinib,gefitinib [cytosol] [Homo sapiens] [DefinedSet:9665127] TKIs (ERBB2) [cytosol] |
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No pathways have been reviewed or authored by Gefitinib [cytosol] (1169429)