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| Class:Id | Summation:1168930 |
|---|---|
| _displayName | In the resting state the luminal domain of STIM1 binds Ca2+ ... |
| _timestamp | 2012-01-27 02:52:16 |
| created | [InstanceEdit:1168936] May, B, 2011-01-11 |
| modified | [InstanceEdit:2076259] May, B, 2012-01-27 |
| text | In the resting state the luminal domain of STIM1 binds Ca2+ ions within the endoplasmic reticulum and this binding prevents dimerization of STIM1 (Luik et al. 2008). Upon depletion of Ca2+ ions from the endoplasmic reticulum, STIM1 is no longer bound to Ca2+ and forms homodimers (Muik et al. 2008, Luik et al. 2008, Park et al. 2009). |
| (summation) | [Reaction:1168376] STIM1 oligomerizes [Homo sapiens] |
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