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Details on Person SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin

Class:Id	LiteratureReference:1168874
_displayName	SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin
_timestamp	2011-01-10 13:24:17
author	[Person:193820] Duan, C [Person:180169] Li, M [Person:1168868] Rui, L
created	[InstanceEdit:1168832] Jupe, S, 2011-01-10
journal	J Biol Chem
pages	43684-91
pubMedIdentifier	15316008
title	SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin
volume	279
year	2004
(literatureReference)	[Summation:178515] Using receptor mutagenesis studies it is known that IRS1 via... [Summation:1168429] GH has short term effects that mimic the actions of insulin... [Reaction:74707] Binding of IRS to insulin receptor [Homo sapiens] [Reaction:2671841] Phosphorylated Lep:Lepr:Jak2:Sh2b1 Binds Irs1/2 [Mus musculus] [Reaction:2671873] Phosphorylated LEP:LEPR:JAK2:SH2B1 Binds IRS1/2 [Homo sapiens]
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No pathways have been reviewed or authored by SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin (1168874)