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Details on Person UniProt:P93844 PLD2
| Class:Id | ReferenceGeneProduct:1162746 |
|---|---|
| _chainChangeLog | chain:1-817 added on Fri February 12 2016 |
| _displayName | UniProt:P93844 PLD2 |
| _timestamp | 2023-11-03 17:33:01 |
| chain | chain:1-817 |
| checksum | 948AE6A40B32E12F |
| comment | FUNCTION Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond. Plays an important role in various cellular processes.CATALYTIC ACTIVITY a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)COFACTOR C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. A lower affinity toward calcium can be anticipated for PLD alpha due to the absence of two potential calcium ligands.SIMILARITY Belongs to the phospholipase D family. C2-PLD subfamily. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| crossReference | [DatabaseIdentifier:1150176] UniProtKB:Q0DB42 [DatabaseIdentifier:1141582] UniProtKB:P93844 |
| description | recommendedName: Phospholipase D alpha 2 shortName: PLD alpha 2 ecNumber: 3.1.4.4 alternativeName: Choline phosphatase 2 alternativeName: Phosphatidylcholine-hydrolyzing phospholipase D 2 |
| geneName | PLD2 Os06g0604400 LOC_Os06g40190 OsJ_21907 P0481H08.5 |
| identifier | P93844 |
| isSequenceChanged | FALSE |
| keyword | Calcium Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Repeat |
| modified | [InstanceEdit:8854446] Gupta, Parul, 2016-01-27 [InstanceEdit:8856987] Weiser, JD [InstanceEdit:8858198] Amarasinghe, Vindhya, 2016-02-17 [InstanceEdit:8869714] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9688885] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | PLD2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PLDA2_ORYSJ A0A0P0WYW9 Q0DB42 Q69X20 |
| sequenceLength | 817 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1127170] phospholipase D [cytosol] [Oryza sativa] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P93844 PLD2 (1162746)
