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Details on Person UniProt:Q9AWZ7 KPHMT2
| Class:Id | ReferenceGeneProduct:1160067 |
|---|---|
| _chainChangeLog | transit peptide:1-90 added on Fri February 6 2015;chain:91-399 added on Fri February 6 2015 |
| _displayName | UniProt:Q9AWZ7 KPHMT2 |
| _timestamp | 2026-02-20 22:36:22 |
| chain | transit peptide:1-90 chain:91-399 |
| checksum | BD28EAD9C97F75CD |
| comment | FUNCTION Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.CATALYTIC ACTIVITY (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolateCOFACTOR Binds 1 Mg(2+) ion per subunit.PATHWAY Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.SUBCELLULAR LOCATION Belongs to the PanB family. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| crossReference | [DatabaseIdentifier:1148492] UniProtKB:A2WM99 [DatabaseIdentifier:1143426] UniProtKB:Q9AWZ7 |
| description | recommendedName: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2, mitochondrial ecNumber: 2.1.2.11 alternativeName: Ketopantoate hydroxymethyltransferase 2 |
| geneName | KPHMT2 PANB2 Os01g0225500 LOC_Os01g12570 P0443E07.7 P0492F05.16 |
| identifier | Q9AWZ7 |
| isSequenceChanged | FALSE |
| keyword | Magnesium Metal-binding Mitochondrion Pantothenate biosynthesis Reference proteome Transferase Transit peptide |
| modified | [InstanceEdit:2871786] D'Eustachio, P, 2012-12-21 [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | KPHMT2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PANB2_ORYSJ A0A0P0UZU4 |
| sequenceLength | 399 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1125369] 3-methyl-2-oxobutanoate hydroxymethyltransferase (LOC_OS01G12570.1) [cytosol] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q9AWZ7 KPHMT2 (1160067)
