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Details on Person UniProt:Q8LIY8 CCD8B
| Class:Id | ReferenceGeneProduct:1159560 |
|---|---|
| _chainChangeLog | transit peptide:1-43 added on Sat February 7 2015;chain:44-569 added on Sat February 7 2015 |
| _displayName | UniProt:Q8LIY8 CCD8B |
| _timestamp | 2025-02-21 19:36:05 |
| chain | transit peptide:1-43 chain:44-569 |
| checksum | AE4E1A0327AEF869 |
| comment | FUNCTION Involved in strigolactones biosynthesis by cleaving the C(27) 9-cis-10'-apo-beta-carotenal produced by CCD7. Produces the C(19) carlactone and a C(8) hydroxyaldehyde. Also shows lower activity with all-trans-10'-apo-beta-carotenal producing a C(9) dialdehyde and the C(18) 13-apo-beta-carotenone. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.CATALYTIC ACTIVITY 9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactoneCATALYTIC ACTIVITY all-trans-10'-apo-beta-carotenal + O2 = (2E,4E,6E)-4-methylocta-2,4,6-trienedial + 13-apo-beta-carotenoneCOFACTOR Binds 1 Fe(2+) ion per subunit.SUBCELLULAR LOCATION Expressed in parenchyma cells of the root stele, shoot apex, leaf buds, xylem parenchyma cells of the stem, inflorescences and panicles.INDUCTION By auxin.DISRUPTION PHENOTYPE Dwarf phenotype with increased branching and tiller number, and strong reduction of the root levels of strigolactones.MISCELLANEOUS The branching phenotypes of the ccd7/max3 and ccd8b/max4 mutants can be rescued by exogenous treatment with the synthetic strigolactone analogs GR24 and 4BD.SIMILARITY Belongs to the carotenoid oxygenase family. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| crossReference | [DatabaseIdentifier:1144433] UniProtKB:A2ZXS1 [DatabaseIdentifier:1143718] UniProtKB:A2WV02 [DatabaseIdentifier:1148579] UniProtKB:Q8LIY8 |
| description | recommendedName: Carotenoid cleavage dioxygenase 8 homolog B, chloroplastic shortName: OsCCD8b ecNumber evidence="9"1.13.11.69 ecNumber evidence="6"1.13.11.70 alternativeName: Protein DWARF-10 alternativeName: Protein MAX4 homolog |
| geneName | CCD8B D10 Os01g0746400 LOC_Os01g54270 OSJNBa0014K08.38 |
| identifier | Q8LIY8 |
| isSequenceChanged | FALSE |
| keyword | Chloroplast Dioxygenase Iron Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide |
| modified | [InstanceEdit:5367723] Amarasinghe, V, 2014-04-25 [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5654781] Amarasinghe, Vindhya, 2014-12-04 [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8856987] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9750299] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | CCD8B |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CCD8B_ORYSJ A0A0P0V860 Q0JJD5 |
| sequenceLength | 569 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1127406] transposon protein (LOC_OS01G54270.1) [Oryza sativa] [EntityWithAccessionedSequence:5367761] CCD8 (LOC_Os01g54270) [plastid stroma] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q8LIY8 CCD8B (1159560)
