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Details on Person UniProt:Q7G602 CYP75B3
| Class:Id | ReferenceGeneProduct:1158539 |
|---|---|
| _displayName | UniProt:Q7G602 CYP75B3 |
| _timestamp | 2025-08-15 22:17:12 |
| chain | chain:1-526 |
| checksum | A039C5A6DA3B3DC7 |
| comment | FUNCTION Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state (PubMed:18726614). Catalyzes the 3'-hydroxylation of apigenin to generate luteolin (Probable).CATALYTIC ACTIVITY a 3'-unsubstituted flavone + reduced [NADPH--hemoprotein reductase] + O2 = a 3'-hydroxyflavone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)COFACTOR Secondary metabolite biosynthesis; flavonoid biosynthesis.SUBCELLULAR LOCATION Induced by light.SIMILARITY Belongs to the cytochrome P450 family. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| crossReference | [DatabaseIdentifier:1138830] UniProtKB:Q8S845 [DatabaseIdentifier:1141384] UniProtKB:Q7G602 [DatabaseIdentifier:1135088] UniProtKB:A2Z5X3 |
| description | recommendedName: fullName evidence="6"Flavonoid 3'-monooxygenase CYP75B3 ecNumber evidence="7"1.14.14.82 alternativeName: fullName evidence="5"Cytochrome P450 75B3 alternativeName: fullName evidence="4"Flavonoid 3'-hydroxylase shortName evidence="4"OsF3'H |
| geneName | CYP75B3 F3'H Os10g0320100 LOC_Os10g17260 OsJ_31048 OSJNAa0053D03.2 OSJNBa0053D03.12 |
| identifier | Q7G602 |
| isSequenceChanged | FALSE |
| keyword | Flavonoid biosynthesis Heme Iron Membrane Metal-binding Monooxygenase NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix |
| modified | [InstanceEdit:1251358] D'Eustachio, P, 2011-04-25 [InstanceEdit:2672435] D'Eustachio, P, 2012-11-27 [InstanceEdit:9015733] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9616384] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | CYP75B3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | C75B3_ORYSJ Q8S845 |
| sequenceLength | 526 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1124404] flavonoid-3-hydroxylase (LOC_OS10G17260.1) [cytosol] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q7G602 CYP75B3 (1158539)
