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Details on Person UniProt:Q7F0Q2 Os07g0493400
| Class:Id | ReferenceGeneProduct:1157967 |
|---|---|
| _chainChangeLog | chain:1-353 added on Fri February 6 2015 |
| _displayName | UniProt:Q7F0Q2 Os07g0493400 |
| _timestamp | 2025-02-21 19:00:30 |
| chain | chain:1-353 |
| checksum | 08E6F432E2DCE6C0 |
| comment | FUNCTION Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol (By similarity). Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism (By similarity). Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation (By similarity).CATALYTIC ACTIVITY a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)PATHWAY Protein modification; protein glycosylation.SUBCELLULAR LOCATION Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| crossReference | [DatabaseIdentifier:1137173] UniProtKB:Q7F0Q2 [DatabaseIdentifier:1136533] UniProtKB:B8B6G5 |
| description | recommendedName: fullName evidence="4"Polyprenal reductase 2 ecNumber evidence="2"1.3.1.94 |
| geneName | Os07g0493400 LOC_Os07g31140 OsJ_24314 P0038F10.126 |
| identifier | Q7F0Q2 |
| isSequenceChanged | FALSE |
| keyword | Cell membrane Membrane NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix |
| modified | [InstanceEdit:2730779] Amarasinghe, V, 2012-12-04 [InstanceEdit:3132113] Weiser, JD [InstanceEdit:3445779] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | Os07g0493400 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PPRD2_ORYSJ A0A0P0X626 |
| sequenceLength | 353 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1128012] 3-oxo-5-alpha-steroid 4-dehydrogenase (LOC_OS07G31140.1) [cytosol] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q7F0Q2 Os07g0493400 (1157967)
