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Details on Person UniProt:P14717 PAL
| Class:Id | ReferenceGeneProduct:1155022 |
|---|---|
| _chainChangeLog | chain:1-701 added on Sat February 7 2015 |
| _displayName | UniProt:P14717 PAL |
| _timestamp | 2023-11-03 15:38:40 |
| chain | chain:1-701 |
| checksum | C6AA7CB8DB4F8EE0 |
| comment | FUNCTION This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.CATALYTIC ACTIVITY L-phenylalanine = (E)-cinnamate + NH4(+)PATHWAY Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1.SUBUNIT Homotetramer.SUBCELLULAR LOCATION Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.SIMILARITY Belongs to the PAL/histidase family. |
| created | [InstanceEdit:1164949] Wu, Guanming, 2010-12-11 |
| description | recommendedName: Phenylalanine ammonia-lyase ecNumber evidence="2"4.3.1.24 |
| geneName | PAL Os02g0626100 LOC_Os02g41630 B1215B07.42 OsJ_07592 P0042D01.1 |
| identifier | P14717 |
| isSequenceChanged | FALSE |
| keyword | Cytoplasm Direct protein sequencing Lyase Phenylalanine catabolism Phenylpropanoid metabolism Reference proteome |
| modified | [InstanceEdit:2882015] D'Eustachio, P, 2012-12-26 [InstanceEdit:3132113] Weiser, JD [InstanceEdit:3240283] D'Eustachio, P, 2013-03-27 [InstanceEdit:3445779] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:6787300] Amarasinghe, Vindhya, 2015-07-10 [InstanceEdit:6791590] Weiser, JD [InstanceEdit:8861963] Naithani, Sushma, 2016-02-22 [InstanceEdit:8869714] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9773244] Weiser, Joel [InstanceEdit:9829221] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | PAL |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PAL1_ORYSJ Q0DZE3 Q6K1Q8 |
| sequenceLength | 701 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:1125701] phenylalanine ammonia-lyase (LOC_OS02G41630.1) [cytosol] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:P14717 PAL (1155022)
