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Details on Person Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7

Class:Id	Reaction:114392
_displayName	Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7
_doRelease	TRUE
_timestamp	2018-11-08 19:49:55
authored	[InstanceEdit:111451] Alnemri, E, 2004-02-17 00:23:30
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:111451] Alnemri, E, 2004-02-17 00:23:30
edited	[InstanceEdit:9627414] Shamovsky, Veronica, 2018-11-02
input	[Complex:114353] DIABLO:XIAP:Caspase-7 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:114476] Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
modified	[InstanceEdit:114471] Matthews, L, 2004-07-28 03:00:00 [InstanceEdit:141637] Matthews, L, 2004-09-23 23:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:213317] Matthews, L, 2008-02-25 10:32:57 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9627414] Shamovsky, Veronica, 2018-11-02 [InstanceEdit:9628219] Shamovsky, Veronica, 2018-11-07 [InstanceEdit:9628510] Shamovsky, Veronica, 2018-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7
output	[Complex:141643] Caspase-7 [cytosol] [Homo sapiens] [Complex:9627391] DIABLO dimer:XIAP [cytosol] [Homo sapiens]
precedingEvent	[Reaction:114354] SMAC binds XIAP:Caspase-7 [Homo sapiens] [Reaction:114307] Release of SMAC (DIABLO) from mitochondria [Homo sapiens]
releaseDate	2004-10-27
reviewed	[InstanceEdit:9627969] Matthews, Lisa, 2018-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358748] R-HSA-114392.4
summation	[Summation:178686] The linker region preceding BIR2 of XIAP is responsible for ...
(hasEvent)	[Pathway:111464] SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes [Homo sapiens] [Pathway:141220] DNR OMI dissociation reactions apoptosis Intrinsic pathway [Homo sapiens]
(inferredFrom)	[Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 [Homo sapiens] [Reaction:114440] Dissociation of DIABLO:XIAP from the apoptosome complex [Homo sapiens]
(precedingEvent)	[Reaction:201628] Caspase-mediated cleavage of vimentin at DSVD (85) [Homo sapiens] [Reaction:201634] Caspase-mediated cleavage of FADK 1 [Homo sapiens] [Reaction:201639] Caspase-mediated cleavage of GAS2 [Homo sapiens] [BlackBoxEvent:9029680] Caspase-7 translocates to the nucleus [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9778745] Update Tracker - [Reaction:114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 - v67:[add_removeOutput, modifyText] [_UpdateTracker:9788043] Update Tracker - [Reaction:114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 - v44:[modifyText]
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