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Details on Person Oligomerization of BAK at the mitochondrial membrane

Class:Id	Reaction:114263
_displayName	Oligomerization of BAK at the mitochondrial membrane
_doRelease	TRUE
_timestamp	2016-11-10 00:57:08
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:139911] Hardwick, JM, Tsujimoto, Y, 2004-08-09 19:10:09
input	[EntityWithAccessionedSequence:50690] BAK1 activated [mitochondrial outer membrane] [Homo sapiens] [EntityWithAccessionedSequence:50690] BAK1 activated [mitochondrial outer membrane] [Homo sapiens]
literatureReference	[LiteratureReference:139821] BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization
modified	[InstanceEdit:114288] Matthews, L, 2004-07-02 10:00:00 [InstanceEdit:114449] Matthews, L, 2004-07-16 10:00:00 [InstanceEdit:139820] Matthews, L, 2004-08-06 15:00:00 [InstanceEdit:139894] Gopinathrao, G, 2004-08-09 18:50:00 [InstanceEdit:141115] Gopinathrao, G, 2004-08-31 17:54:38 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Oligomerization of BAK at the mitochondrial membrane
output	[Complex:114262] Active oligomeric BAK [mitochondrial outer membrane] [Homo sapiens]
precedingEvent	[Reaction:139895] tBID activates BAK protein [Homo sapiens] [Reaction:168848] tBID binds to inactive BAK protein [Homo sapiens]
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360015] R-HSA-114263.3
summation	[Summation:179007] Once activated BAK insterts in the outer mitochondrial membr...
(hasEvent)	[Pathway:111452] Activation and oligomerization of BAK protein [Homo sapiens]
(precedingEvent)	[Reaction:114284] Release of Cytochrome c from mitochondria [Homo sapiens] [Reaction:114307] Release of SMAC (DIABLO) from mitochondria [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787640] Update Tracker - [Reaction:114263] Oligomerization of BAK at the mitochondrial membrane - v44:[modifyText]
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No pathways have been reviewed or authored by Oligomerization of BAK at the mitochondrial membrane (114263)