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Details on Person CYCS binds to APAF1

Class:IdReaction:114254
_displayNameCYCS binds to APAF1
_doReleaseTRUE
_timestamp2018-11-08 19:49:07
compartment[Compartment:70101] cytosol
created[InstanceEdit:111451] Alnemri, E, 2004-02-17 00:23:30
edited[InstanceEdit:9628204] Shamovsky, Veronica, 2018-11-07
input[EntityWithAccessionedSequence:53259] CYCS [cytosol] [Homo sapiens]
[Complex:9627055] APAF1:ADP [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:141213] Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
[LiteratureReference:9627065] Apaf-1: Regulation and function in cell death
[LiteratureReference:9627378] Changes in Apaf-1 conformation that drive apoptosome assembly
modified[InstanceEdit:141211] Matthews, L, 0000-00-00 00:00:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:8861948] Orlic-Milacic, Marija, 2016-02-22
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9029237] Orlic-Milacic, Marija, 2017-11-14
[InstanceEdit:9627057] Shamovsky, Veronica, 2018-11-01
[InstanceEdit:9627414] Shamovsky, Veronica, 2018-11-02
[InstanceEdit:9628219] Shamovsky, Veronica, 2018-11-07
[InstanceEdit:9628510] Shamovsky, Veronica, 2018-11-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCYCS binds to APAF1
output[Complex:6804555] APAF1:ATP:CYCS [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2004-10-27
reviewed[InstanceEdit:9620504] Matthews, Lisa, 2018-09-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361674] R-HSA-114254.6
summation[Summation:178623] The apoptotic protease‑activating factor 1 (APAF1) is a cyto...
(hasEvent)[Pathway:111458] Formation of apoptosome [Homo sapiens]
(precedingEvent)[Reaction:114256] CYCS:APAF1 binds procaspase-9 [Homo sapiens]
[Reaction:6804579] APAF1:CYCS forms heptamer [Homo sapiens]
(updatedInstance)[_UpdateTracker:9778952] Update Tracker - [Reaction:114254] CYCS binds to APAF1 - v67:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[_UpdateTracker:9787699] Update Tracker - [Reaction:114254] CYCS binds to APAF1 - v44:[modifyText]
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