Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person It has been observed in Drosophila that E2F1 regulates expr...
| Class:Id | Summation:113658 |
|---|---|
| _displayName | It has been observed in Drosophila that E2F1 regulates expr... |
| _timestamp | 2004-09-20 13:52:48 |
| created | [InstanceEdit:113655] Gopinathrao, G, 2004-06-14 19:10:00 |
| literatureReference | [LiteratureReference:113659] E2F mediates developmental and cell cycle regulation of ORC1 in Drosophila |
| modified | [InstanceEdit:141448] Matthews, L, 2004-09-20 15:43:00 |
| text | It has been observed in Drosophila that E2F1 regulates expression of Orc1, stimulates ORC1-6 complex formation and binding to origin of replication (Asano and Wharton, 1999). Orc1-6 recruit Cdc6 and Cdt1 that are required to recruit the MCM2-7 replication helicases. E2F1 regulation incorporates a feedback mechanism where in Geminin can inhibit MCM2-7 recruitment on ORC1-6 complex by interacting with Cdc6/Cdt1 . |
| (summation) | [BlackBoxEvent:113632] Expression of ORC1 [Homo sapiens] |
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No pathways have been reviewed or authored by It has been observed in Drosophila that E2F1 regulates expr... (113658)
