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Details on Person This reaction has been inferred from a similar event in Dros...
| Class:Id | Summation:113508 |
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| _displayName | This reaction has been inferred from a similar event in Dros... |
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| _timestamp | 2006-01-13 18:54:17 |
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| created | [InstanceEdit:113497] Gopinathrao, G, 2004-05-26 17:05:00 |
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| literatureReference | [LiteratureReference:113615] Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing
[LiteratureReference:141352] Serum-induced expression of the cdc25A gene by relief of E2F-mediated repression
[LiteratureReference:141377] CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase |
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| modified | [InstanceEdit:113655] Gopinathrao, G, 2004-06-14 19:10:00
[InstanceEdit:113686] Gopinathrao, G, 2004-06-16 19:20:00
[InstanceEdit:141358] Gopinathrao, G, 2004-09-16 18:17:41
[InstanceEdit:159088] Gopinathrao, G, 2005-02-16 22:13:27
[InstanceEdit:170720] D'Eustachio, P, 2006-01-13 18:54:09 |
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| text | This reaction has been inferred from a similar event in Drosophila as observed by Reis and Edgar (2004). E2F1 activates string (cdc25) that in turn activates Cyclin B/Cdk1. A similar phenomenon has been observed in mouse NIH 3T3 cells by Chen and Prywes (1999) and in Rat1 cells by Vigo et al (1999). |
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| (summation) | [BlackBoxEvent:113498] Activation of Cdc25a (string) by E2F1 [Homo sapiens] |
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No pathways have been reviewed or authored by This reaction has been inferred from a similar event in Dros... (113508)
