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Details on Person RNA Polymerase III Termination and release of transcribed RNA
Class:Id Reaction:113454
_displayName RNA Polymerase III Termination and release of transcribed RNA
_doRelease TRUE
_timestamp 2016-11-10 00:57:11
authored [InstanceEdit:111982] Geiduschek, E, 2004-03-29 17:50:49
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:111619] Kassavetis, GA, Geiduschek, EP, 2004-02-27 13:21:23
edited [InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
goBiologicalProcess [GO_BiologicalProcess:17891] termination of RNA polymerase III transcription
inferredFrom
input [Complex:113453] Paused RNA Polymerase III Transcription Complex [nucleoplasm] [Homo sapiens] [OtherEntity:112475] paused pre-RNA Pol III transcript [nucleoplasm]
literatureReference [LiteratureReference:112460] La proteins from Drosophila melanogaster and Saccharomyces cerevisiae: a yeast homolog of the La autoantigen is dispensable for growth. [LiteratureReference:112461] DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III. [LiteratureReference:112462] Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. [LiteratureReference:112142] Analysis of RNA chain elongation and termination by Saccharomyces cerevisiae RNA polymerase III.
modified [InstanceEdit:114227] Joshi-Tope, G, 2004-06-28 00:11:52 [InstanceEdit:141273] Gillespie, ME, 2004-09-09 20:51:48 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:749477] Gillespie, ME, 2010-05-18 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:6784590] May, Bruce, 2015-06-21 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name RNA Polymerase III Termination and release of transcribed RNA
output [OtherEntity:113448] Polymerase III gene DNA with a termination site [nucleoplasm] [OtherEntity:112478] released pre-RNA Pol III transcript [nucleoplasm] [Complex:83716] RNA Polymerase III Holoenzyme [nucleoplasm] [Homo sapiens]
regulatedBy [PositiveRegulation:113456] Positive regulation by 'NFIX [nucleoplasm]' [PositiveRegulation:113458] Positive regulation by 'SSB [nucleoplasm]' [PositiveRegulation:113459] Positive regulation by 'NFIA [nucleoplasm]' [PositiveRegulation:113460] Positive regulation by 'NFIB [nucleoplasm]' [PositiveRegulation:113461] Positive regulation by 'NFIC [nucleoplasm]'
regulationReference [RegulationReference:9641682] Positive regulation by 'NFIX [nucleoplasm]' Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. [RegulationReference:9642208] Positive regulation by 'NFIA [nucleoplasm]' Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. [RegulationReference:9642697] Positive regulation by 'NFIC [nucleoplasm]' Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. [RegulationReference:9642992] Positive regulation by 'SSB [nucleoplasm]' Recognition of nascent RNA by the human La antigen: conserved and divergent features of structure and function. [RegulationReference:9643020] Positive regulation by 'NFIB [nucleoplasm]' Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III.
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:361325] R-HSA-113454.7
summation [Summation:113455] Efficient transcript production requires efficient release o... [Summation:113457] The biochemically purified NF1 family proteins exert strong ...
(hasEvent) [Pathway:73980] RNA Polymerase III Transcription Termination [Homo sapiens] [Pathway:749476] RNA Polymerase III Abortive And Retractive Initiation [Homo sapiens]
(inferredFrom) [Reaction:1113257] RNA Polymerase III Termination and release of transcribed RNA [Oryza sativa]
(orthologousEvent) [Reaction:1113257] RNA Polymerase III Termination and release of transcribed RNA [Oryza sativa]
(precedingEvent) [Reaction:5696810] RNase P cleaves the 5' end of pre-tRNA [Homo sapiens] [Reaction:6782311] ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs [Homo sapiens]
(updatedInstance) [_UpdateTracker:9775744] Update Tracker - [Reaction:113454] RNA Polymerase III Termination and release of transcribed RNA - v78:[addSummation]
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