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Details on Person P-TEFb complex [nucleoplasm]

Class:IdComplex:112431
_displayNameP-TEFb complex [nucleoplasm]
_timestamp2015-11-02 09:03:56
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:112414] Gopinathrao, G, 2004-05-03 18:16:42
hasComponent
literatureReference[LiteratureReference:6807465] P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA
modified[InstanceEdit:113792] Gopinathrao, G, 2004-06-22 14:12:50
[InstanceEdit:170259] Matthews, L, 2006-01-03 21:23:50
[InstanceEdit:6807468] May, Bruce, 2015-11-02
nameP-TEFb complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:370956] R-HSA-112431.2
(activeUnit)[CatalystActivity:6814557] protein serine/threonine kinase activity of RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
[Requirement:9685236] Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]'
(hasComponent)[Complex:113426] Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] [Homo sapiens]
[Complex:113719] Processive elongation complex [nucleoplasm] [Homo sapiens]
[Complex:113720] Paused processive elongation complex [nucleoplasm] [Homo sapiens]
[Complex:113721] Arrested processive elongation complex [nucleoplasm] [Homo sapiens]
[Complex:113722] Aborted elongation complex after arrest [nucleoplasm] [Homo sapiens]
[Complex:113724] Elongation complex prior to separation [nucleoplasm] [Homo sapiens]
[Complex:113726] Elongation complex with separated and uncleaved transcript [nucleoplasm] [Homo sapiens]
[Complex:167075] HIV-1 early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] [Homo sapiens]
[Complex:167081] HIV-1 processive elongation complex [nucleoplasm] [Homo sapiens]
[Complex:167143] HIV-1 elongation complex prior to separation [nucleoplasm] [Homo sapiens]
List all 18 refering instances
(hasMember)[DefinedSet:2176485] CDK8:CCNC/ CDK9:CCNT [nucleoplasm] [Homo sapiens]
(input)[Reaction:112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex [Homo sapiens]
[Reaction:167084] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex [Homo sapiens]
[Reaction:6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene [Homo sapiens]
(output)[Reaction:112430] Formation of P-TEFb complex [Homo sapiens]
[Reaction:113429] Elongating transcript encounters a lesion in the template [Homo sapiens]
[Reaction:5652025] P-TEFb disassociates from the 7SK snRNP Complex [Homo sapiens]
(physicalEntity)[CatalystActivity:113431] protein serine/threonine kinase activity of P-TEFb complex [nucleoplasm]
(updatedInstance)[_UpdateTracker:9893269] Update Tracker - [Complex:112431] P-TEFb complex [nucleoplasm] - v55:[addLiteratureReference, add_removeHasComponent]
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No pathways have been reviewed or authored by P-TEFb complex [nucleoplasm] (112431)
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