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Details on Person Hypophosphorylation of RNA Pol II CTD by FCP1P protein

Class:Id	Reaction:112383
_displayName	Hypophosphorylation of RNA Pol II CTD by FCP1P protein
_doRelease	TRUE
_timestamp	2016-11-10 00:57:03
authored	[InstanceEdit:112380] Gopinathrao, G, 2004-04-28 10:54:00
catalystActivity	[CatalystActivity:113432] phosphoprotein phosphatase activity of CTDP1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75957] Conaway, JW, Conaway, RC, 2003-09-11
input	[Complex:77089] capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:113416] CTDP1 [nucleoplasm] [Homo sapiens] [Complex:109634] TFIIH [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:113810] FCP1, a phosphatase specific for the heptapeptide repeat of the largest subunit of RNA polymerase II, stimulates transcription elongation. [LiteratureReference:6814946] FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO
modified	[InstanceEdit:113400] Gopinathrao, G, 2004-05-06 22:00:00 [InstanceEdit:113713] Gopinathrao, G, 2004-06-20 19:55:54 [InstanceEdit:113852] Joshi-Tope, G, 2004-06-23 21:17:01 [InstanceEdit:159385] Gopinathrao, G, 2005-03-07 19:22:08 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:6787489] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:6814947] May, Bruce, 2015-11-30 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hypophosphorylation of RNA Pol II CTD by FCP1P protein
output	[Complex:113715] RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] [Homo sapiens] [Complex:109634] TFIIH [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:77095] Recognition and binding of the mRNA cap by the cap-binding complex [Homo sapiens] [Reaction:77090] Methylation of GMP-cap by RNA Methyltransferase [Homo sapiens] [Reaction:77094] Formation of cap binding complex (CBC) [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361535] R-HSA-112383.5
summation	[Summation:112393] FCP1 dephosphorylates RNAP II in ternary elongation complexe...
(hasEvent)	[Pathway:113418] Formation of the Early Elongation Complex [Homo sapiens]
(inferredFrom)	[Reaction:167072] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens] [Reaction:1113102] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Oryza sativa] [BlackBoxEvent:6814554] Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene [Homo sapiens]
(orthologousEvent)	[Reaction:1113102] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Oryza sativa]
(precedingEvent)	[Reaction:113407] DSIF complex binds to RNA Pol II (hypophosphorylated) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783605] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v56:[addLiteratureReference, modifyText] [_UpdateTracker:9784135] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v54:[addLiteratureReference]
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