Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SRC autophosphorylation is positively regulated by InlA-bound CDH1

Class:Id	BlackBoxEvent:112333
_displayName	SRC autophosphorylation is positively regulated by InlA-bound CDH1
_doRelease	TRUE
_timestamp	2023-05-25 21:55:09
authored	[InstanceEdit:8876400] Orlic-Milacic, Marija, 2016-06-14
catalystActivity	[CatalystActivity:8876921] protein tyrosine kinase activity of MyrG-SRC [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:112400] Charalambous, M, 2004-04-29 09:21:24
disease	[Disease:8875363] listeriosis
edited	[InstanceEdit:8943577] Orlic-Milacic, Marija, 2016-10-26
entityOnOtherCell	[EntityWithAccessionedSequence:8876505] InlA [Gram-positive-bacterium-type cell wall] [Listeria monocytogenes]
input	[EntityWithAccessionedSequence:8876922] MyrG-SRC [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:112334] Regulation, substrates and functions of src. [LiteratureReference:8876932] Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells
modified	[InstanceEdit:112397] Schmidt, EE, 2004-04-29 09:21:20 [InstanceEdit:163616] Schmidt, EE, 2005-05-03 09:53:07 [InstanceEdit:188727] D'Eustachio, P, 2006-10-26 15:45:31 [InstanceEdit:8876919] Orlic-Milacic, Marija, 2016-06-17 [InstanceEdit:8876936] Orlic-Milacic, Marija, 2016-06-17 [InstanceEdit:8876968] Orlic-Milacic, Marija, 2016-06-17 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933575] Orlic-Milacic, Marija, 2016-08-08 [InstanceEdit:8943566] Orlic-Milacic, Marija, 2016-10-26 [InstanceEdit:8943578] Orlic-Milacic, Marija, 2016-10-26 [InstanceEdit:8948175] Orlic-Milacic, Marija, 2016-11-11 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9836317] D'Eustachio, Peter, 2023-05-25
name	SRC autophosphorylation is positively regulated by InlA-bound CDH1
output	[EntityWithAccessionedSequence:1810408] MyrG-p-Y419-SRC [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:8876497] InlA binds CDH1 [Homo sapiens]
regulatedBy	[PositiveRegulation:8876920] Positive regulation by 'InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]'
relatedSpecies	[Species:8875362] Listeria monocytogenes
releaseDate	2016-12-12
reviewed	[InstanceEdit:8943564] Schwerk, Christian, 2016-10-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8896106] R-HSA-112333.4
summation	[Summation:8876950] SRC activation involves autophosphorylation at tyrosine resi...
(hasEvent)	[Pathway:8876493] InlA-mediated entry of Listeria monocytogenes into host cells [Homo sapiens]
(precedingEvent)	[Reaction:163334] (Controversial - not included in public release. )Src phosphorylates RAF [Homo sapiens] [BlackBoxEvent:8876948] SRC phosphorylates InlA-bound CDH1 and CTNNB1 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by SRC autophosphorylation is positively regulated by InlA-bound CDH1 (112333)