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Details on Person DAGs [plasma membrane]
| Class:Id | SimpleEntity:112275 |
| _displayName | DAGs [plasma membrane] |
| _timestamp | 2012-10-26 21:06:33 |
| compartment | [Compartment:876] plasma membrane |
| created | [InstanceEdit:112274] Schmidt, EE, 2004-04-19 12:06:05 |
| crossReference | [DatabaseIdentifier:29669] COMPOUND:C00165 |
| modified | [InstanceEdit:182105] Jassal, Bijay, 2006-07-06 [InstanceEdit:191099] Jassal, B, 2007-01-18 11:57:34 [InstanceEdit:198310] 2007-07-10 08:01:55 [InstanceEdit:211326] D'Eustachio, P, 2008-01-31 15:47:44 [InstanceEdit:429791] D'Eustachio, P, 2009-07-21 [InstanceEdit:2024076] Williams, MG, 2011-12-13 [InstanceEdit:2537470] Wu, G, 2012-10-26 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19 |
| name | DAGs diacylglycerols diglyceride DAG |
| referenceEntity | [ReferenceMolecule:174723] diglyceride [ChEBI:18035] |
| stableIdentifier | [StableIdentifier:366879] R-ALL-112275.3 |
| (hasComponent) | [Complex:202187] PKC-theta (open): DAG [plasma membrane] [Homo sapiens] [Complex:202300] p-Y90-PKC-theta:DAG [plasma membrane] [Homo sapiens] [Complex:202442] Active PKC theta bound to DAG [plasma membrane] [Homo sapiens] [Complex:392840] CalDAG-GEF 1/3:DAG [plasma membrane] [Homo sapiens] [Complex:1169551] p-Rasgrp1,3:DAG [plasma membrane] [Mus musculus] [Complex:2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Homo sapiens] [Complex:2685677] RasGRP1:DAG:Ca2+ [plasma membrane] [Mus musculus] [Complex:2685686] RasGRPs:DAG:Ca2+ [plasma membrane] [Homo sapiens] [Complex:5218773] DAG:active PKC:Ca+2 [plasma membrane] [Homo sapiens] [Complex:5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Homo sapiens] |
| (hasMember) | [DefinedSet:392524] Calcium and DAG [plasma membrane] [Homo sapiens] |
| (input) | [Reaction:202328] Translocation of PKC theta to plasma membrane [Homo sapiens] [BlackBoxEvent:1169494] Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated [Mus musculus] [Reaction:2730865] RasGRP interacts with DAG and Ca2+ [Mus musculus] [Reaction:2730871] RasGRP interacts with DAG and Ca2+ [Homo sapiens] [Reaction:5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Homo sapiens] [Reaction:5607734] PKC-delta translocates to plasma membrane [Homo sapiens] |
| (output) | [Reaction:111879] PIP2 hydrolysis [Homo sapiens] [Reaction:182061] Active Plcg1 hydrolyses PIP2 [Rattus norvegicus] [Reaction:202407] PLC-gamma1 hydrolyses PIP2 [Homo sapiens] [Reaction:622382] PIP2 hydrolysis [Homo sapiens] [Reaction:622387] PIP2 hydrolysis [Rattus norvegicus] [Reaction:2029468] Conversion of PA into DAG by PAP-1 [Homo sapiens] [Reaction:2730847] Hydrolysis of PIP2 by PLCG [Homo sapiens] [Reaction:5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Homo sapiens] [Reaction:9032476] Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [Mus musculus] [Reaction:9032478] EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate [Homo sapiens] |
| (regulator) | [PositiveRegulation:111888] Positive regulation by 'DAGs [plasma membrane]' [PositiveRegulation:8855329] Positive regulation by 'DAGs [plasma membrane]' [PositiveRegulation:8855331] Positive regulation by 'DAGs [plasma membrane]' |
| (requiredInputComponent) | [Reaction:5218805] PKC autophosphorylates [Homo sapiens] |
| (updatedInstance) | [_UpdateTracker:9866609] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v24:[addReferenceEntity] [_UpdateTracker:9868238] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v30:[modifyName] [_UpdateTracker:9874250] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v43:[addName] [_UpdateTracker:9891794] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v52:[addName] |
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No pathways have been reviewed or authored by DAGs [plasma membrane] (112275)