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Details on Person Activation of PKC (alpha, beta, gamma)

Class:Id	Reaction:112004
_displayName	Activation of PKC (alpha, beta, gamma)
_doRelease	FALSE
_timestamp	2016-07-15 23:49:09
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:111852] Schmidt, EE, 2004-03-24 06:49:11
input	[DefinedSet:111999] Protein kinase C, conventional isoforms (alpha, beta-1, beta-2, gamma) [cytosol] [Homo sapiens] [SimpleEntity:74016] Ca2+ [cytosol]
literatureReference	[LiteratureReference:111948] Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications.
modified	[InstanceEdit:111947] Schmidt, EE, 2004-03-26 09:35:25 [InstanceEdit:111990] Schmidt, EE, 2004-03-31 05:19:10 [InstanceEdit:706453] Jassal, B, 2010-05-10 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19
name	Activation of PKC (alpha, beta, gamma)
output	[Complex:112000] Protein Kinase C, conventional isoforms (alpha, beta, gamma):Ca2+ [cytosol] [Homo sapiens]
precedingEvent	[Reaction:169683] IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol [Homo sapiens] [Reaction:169680] IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel [Homo sapiens] [Reaction:167686] Active PLCG1 hydrolyses PIP2 [Homo sapiens]
regulatedBy	[PositiveRegulation:111887] Positive regulation by 'PS [plasma membrane]' [PositiveRegulation:111888] Positive regulation by 'DAGs [plasma membrane]' [PositiveRegulation:111991] Positive regulation by 'AA [cytosol]'
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8887384] R-HSA-112004.1
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No pathways have been reviewed or authored by Activation of PKC (alpha, beta, gamma) (112004)