Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person dihydrofolate reductase

Class:IdReaction:1120019
_displayNamedihydrofolate reductase
_doReleaseTRUE
_timestamp2016-07-15 23:49:59
catalystActivity[CatalystActivity:1118877] dihydrofolate reductase activity of dihydrofolate reductase [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference[DatabaseIdentifier:1146742] RiceCyc:DIHYDROFOLATEREDUCT-RXN
[DatabaseIdentifier:26862] EC:1.5.1.3
input[SimpleEntity:73604] DHF [cytosol]
[SimpleEntity:29364] NADPH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
modified[InstanceEdit:2873210] D'Eustachio, P, 2012-12-21
[InstanceEdit:2874303] D'Eustachio, P, 2012-12-21
[InstanceEdit:4549280] D'Eustachio, P, 2013-09-11
[InstanceEdit:5376567] D'Eustachio, Peter, 2014-04-28
[InstanceEdit:8879177] Wu, G, 2016-07-15
namedihydrofolate reductase
Tetrahydrofolate dehydrogenase
biochemicalReaction79703
output[SimpleEntity:29366] NADP+ [cytosol]
[SimpleEntity:111355] THF [cytosol]
precedingEvent
species[Species:186860] Oryza sativa
stableIdentifier[StableIdentifier:8909152] R-OSA-1120019.1
summation[Summation:2873191] 7,8-dihydrofolate is converted to tetrahydrofolate by enzyma...
(hasEvent)[Pathway:1119265] Tetrahydrofolate biosynthesis I [Oryza sativa]
[Pathway:1119306] formylTHF biosynthesis II [Oryza sativa]
[Pathway:1119504] formylTHF biosynthesis I [Oryza sativa]
[Pathway:1119523] Tetrahydrofolate biosynthesis II [Oryza sativa]
(precedingEvent)[Reaction:1119640] folylpolyglutamate synthetase [Oryza sativa]
[Reaction:1120801] glycine+tetrahydrofolate+NAD+->ammonia+5,10-methylene-THF+CO2+NADH [Oryza sativa]
[Reaction:1120960] tetrahydrofolate synthase [Oryza sativa]
[Reaction:1121174] Glycine hydroxymethyltransferase [Oryza sativa]
[Reaction:2871176] Glycine hydroxymethyltransferase II [Oryza sativa]
[Change default viewing format]
No pathways have been reviewed or authored by dihydrofolate reductase (1120019)