Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person CaMK4 phosphorylates CREB1
Class:Id Reaction:111912
_displayName CaMK4 phosphorylates CREB1
_doRelease TRUE
_timestamp 2018-11-08 16:59:02
authored [InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05 [InstanceEdit:445353] Mahajan, SS, 2009-10-29
catalystActivity [CatalystActivity:111908] calcium/calmodulin-dependent protein kinase activity of p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:111899] Schmidt, EE, 2004-03-25 09:46:54
edited [InstanceEdit:379927] Jassal, Bijay, 2008-11-06 [InstanceEdit:422554] Gillespie, ME, 2009-06-02 00:56:21 [InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
inferredFrom
input [EntityWithAccessionedSequence:52777] CREB1 [nucleoplasm] [Homo sapiens] [SimpleEntity:29358] ATP [nucleoplasm]
literatureReference [LiteratureReference:443482] Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine
modified [InstanceEdit:113474] Schmidt, EE, 2004-05-20 07:56:43 [InstanceEdit:113791] Schmidt, EE, 2004-06-22 11:07:51 [InstanceEdit:188621] Jassal, Bijay, 2006-10-19 [InstanceEdit:351351] Jassal, B, 2008-05-22 10:22:25 [InstanceEdit:379807] Jassal, B, 2008-11-05 15:52:07 [InstanceEdit:379936] Jassal, Bijay, 2008-11-06 [InstanceEdit:2565867] D'Eustachio, P, 2012-11-08 [InstanceEdit:5210064] May, B, 2013-12-07 [InstanceEdit:5663311] May, Bruce, 2015-01-17 [InstanceEdit:6789298] Jupe, Steve, 2015-07-30 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8979389] May, Bruce, 2017-02-26 [InstanceEdit:9615339] Orlic-Milacic, Marija, 2018-08-01 [InstanceEdit:9615340] Orlic-Milacic, Marija, 2018-08-01 [InstanceEdit:9620229] Orlic-Milacic, Marija, 2018-09-21 [InstanceEdit:9628237] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628240] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628306] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628439] Orlic-Milacic, Marija, 2018-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name CaMK4 phosphorylates CREB1
output [EntityWithAccessionedSequence:111910] p-S133-CREB1 [nucleoplasm] [Homo sapiens] [SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent
releaseDate 2008-12-17
reviewed [InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54 [InstanceEdit:5210062] Lezza, Angela M S, 2013-12-07 [InstanceEdit:446792] Tukey, D, 2009-11-17 [InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8891967] R-HSA-111912.4
summation [Summation:379800] The cAMP-responsive element binding protein (CREB), a key re...
(hasEvent) [Pathway:111932] CaMK IV-mediated phosphorylation of CREB [Homo sapiens] [Pathway:442729] CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde [Homo sapiens] [Pathway:2151201] Transcriptional activation of mitochondrial biogenesis [Homo sapiens] [Pathway:9614083] CREB1-mediated transcription in neuronal development [Homo sapiens]
(precedingEvent) [Reaction:111916] Dimerization of p-S133-CREB1 [Homo sapiens] [BlackBoxEvent:1368140] Expression of PPARGC1A (PGC-1alpha) [Homo sapiens]
(replacementInstances) [_Deleted:9615342] Deletion of instance: 443480
(updatedInstance) [_UpdateTracker:9778909] Update Tracker - [Reaction:111912] CaMK4 phosphorylates CREB1 - v67:[modifyText] [_UpdateTracker:9779056] Update Tracker - [Reaction:111912] CaMK4 phosphorylates CREB1 - v66:[addLiteratureReference, modifyText]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by CaMK4 phosphorylates CREB1 (111912)