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Details on Person PIP2 hydrolysis

Class:IdReaction:111879
_displayNamePIP2 hydrolysis
_doReleaseTRUE
_timestamp2012-12-13 15:39:43
authored[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
catalystActivity[CatalystActivity:111871] phosphatidylinositol-4,5-bisphosphate phospholipase C activity of Activated PLC beta 1/4 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:111852] Schmidt, EE, 2004-03-24 06:49:11
edited[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
input[SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
[SimpleEntity:29356] H2O [cytosol]
literatureReference[LiteratureReference:374860] Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1)
modified[InstanceEdit:112274] Schmidt, EE, 2004-04-19 12:06:05
[InstanceEdit:374877] Jassal, Bijay, 2008-08-05
[InstanceEdit:379936] Jassal, Bijay, 2008-11-06
[InstanceEdit:422154] D'Eustachio, P, 2009-05-26 22:22:55
[InstanceEdit:660810] D'Eustachio, P, 2010-05-01
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:2851312] Jupe, S, 2012-12-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePIP2 hydrolysis
output[SimpleEntity:112275] DAGs [plasma membrane]
[SimpleEntity:114520] I(1,4,5)P3 [cytosol]
precedingEvent
releaseDate2008-12-17
reviewed[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387616] R-HSA-111879.2
summation[Summation:374865] The phospholipase C (PLC) family of enzymes is both diverse ...
(hasEvent)[Pathway:112043] PLC beta mediated events [Homo sapiens]
(precedingEvent)[Reaction:169680] IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787619] Update Tracker - [Reaction:111879] PIP2 hydrolysis - v44:[add_removeInput]
[_UpdateTracker:9790560] Update Tracker - [Reaction:111879] PIP2 hydrolysis - v33:[add_removeOutput]
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No pathways have been reviewed or authored by PIP2 hydrolysis (111879)