Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person THF [cytosol]

Class:IdSimpleEntity:111355
_displayNameTHF [cytosol]
_timestamp2021-07-06 22:31:31
compartment[Compartment:70101] cytosol
created[InstanceEdit:111352] D'Eustachio, P, 2004-02-12 16:37:00
crossReference[DatabaseIdentifier:29545] COMPOUND:C00101
modified[InstanceEdit:197987] Jassal, B, 2007-05-16 09:27:22
[InstanceEdit:2537470] Wu, G, 2012-10-26
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
[InstanceEdit:9736313] D'Eustachio, Peter, 2021-07-06
nameTHF
Tetrahydrofolate
(6S)-5,6,7,8-tetrahydrofolic acid
5,6,7,8-tetrahydrofolate
tetrahydrofolic acid
(6S)-5,6,7,8-tetrahydrofolate(2-)
referenceEntity[ReferenceMolecule:5316165] (6S)-5,6,7,8-tetrahydrofolate(2-) [ChEBI:57453]
stableIdentifier[StableIdentifier:367904] R-ALL-111355.4
(input)[Reaction:70920] N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate [Homo sapiens]
[Reaction:197958] FPGS-2 transforms THF to THFPG [Homo sapiens]
[Reaction:200680] SLC25A32 transports THF from cytosol to mitochondrial matrix [Homo sapiens]
[Reaction:1120232] Formate--tetrahydrofolate ligase [Oryza sativa]
[Reaction:1120960] tetrahydrofolate synthase [Oryza sativa]
[Reaction:1121174] Glycine hydroxymethyltransferase [Oryza sativa]
(output)[Reaction:73798] AICAR + 10-Formyl-THF => FAICAR + THF [Homo sapiens]
[Reaction:73813] GAR + 10-Formyl-THF => FGAR + THF [Homo sapiens]
[Reaction:197972] DHF is reduced to tetrahydrofolate (THF) [Homo sapiens]
[Reaction:200720] SLC25A32 transports THF from mitochondrial matrix to cytosol [Homo sapiens]
[Reaction:419145] 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate [Gallus gallus]
[Reaction:419254] 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate [Gallus gallus]
[Reaction:1113106] AICAR + 10-Formyl-THF => FAICAR + THF [Oryza sativa]
[Reaction:1119703] 3-methyl-2-oxobutanoate hydroxymethyltransferase [Oryza sativa]
[Reaction:1120019] dihydrofolate reductase [Oryza sativa]
[Reaction:1121522] phosphoribosylglycinamide formyltransferase [Oryza sativa]
List all 12 refering instances
(updatedInstance)[_UpdateTracker:9866401] Update Tracker - [SimpleEntity:111355] THF [cytosol] - v22:[modifyName]
[_UpdateTracker:9891827] Update Tracker - [SimpleEntity:111355] THF [cytosol] - v52:[addName]
[_UpdateTracker:9902765] Update Tracker - [SimpleEntity:111355] THF [cytosol] - v78:[addName, add_removeReferenceEntity]
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No pathways have been reviewed or authored by THF [cytosol] (111355)