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Details on Person Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]

Class:Id	Complex:1112594
_displayName	Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
_timestamp	2011-11-23 11:29:56
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1112527] Jupe, S, 2010-12-03
hasComponent	[DefinedSet:1112584] IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] [Homo sapiens] [DefinedSet:1112584] IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:1843855] Jupe, S, 2011-10-28
name	Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1225475] R-HSA-1112594.1
(hasComponent)	[Complex:1112524] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] [Homo sapiens] [Complex:1112576] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] [Homo sapiens] [Complex:1112718] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] [Homo sapiens] [Complex:1112753] IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] [Homo sapiens] [Complex:1112758] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] [Homo sapiens] [Complex:1112759] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] [Homo sapiens] [Complex:9958926] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] [Homo sapiens] [Complex:9958930] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] [Homo sapiens]
(input)	[Reaction:1112565] Tyrosine phosphorylated IL6ST binds STAT1,STAT3 [Homo sapiens] [Reaction:1112708] PTPN11 binds p-Y759-IL6ST [Homo sapiens] [Reaction:1112755] SOCS3 binds IL6ST [Homo sapiens] [Reaction:9958878] Tyrosine phosphorylated IL6ST binds STAT3 [Homo sapiens]
(output)	[BlackBoxEvent:1112510] IL6ST is tyrosine phosphorylated [Homo sapiens] [Reaction:1112604] Phosphorylated STATs are released [Homo sapiens] [Reaction:9958877] p-Y705-STAT3 dissociates from IL6 receptor [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9871145] Update Tracker - [Complex:1112594] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] - v39:[modifyName, updateContainedComponent] [_UpdateTracker:9877346] Update Tracker - [Complex:1112594] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] - v44:[updateContainedComponent] [_UpdateTracker:9896215] Update Tracker - [Complex:1112594] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] - v60:[updateContainedComponent]
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