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Details on Person STAT1 and STAT3 dimers translocate to the nucleus

Class:Id	BlackBoxEvent:1112587
_displayName	STAT1 and STAT3 dimers translocate to the nucleus
_doRelease	TRUE
_timestamp	2017-11-07 16:13:57
authored	[InstanceEdit:1164950] Ray, K, 2010-12-13
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:1112527] Jupe, S, 2010-12-03
edited	[InstanceEdit:1112767] Jupe, S, 2010-12-10
input	[DefinedSet:1112537] p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y701-STAT1:p-Y705-STAT3 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1112562] Requirement of serine phosphorylation for formation of STAT-promoter complexes
modified	[InstanceEdit:1164953] Jupe, S, 2010-12-13 [InstanceEdit:1214160] Jupe, S, 2011-02-11 [InstanceEdit:8963884] Jupe, Steve, 2017-02-13 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9028437] Jupe, Steve, 2017-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	STAT1 and STAT3 dimers translocate to the nucleus
output	[DefinedSet:1112574] STAT1/3 homo and heterodimers [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1112538] Phosphorylated STAT1, STAT3 form dimers [Homo sapiens] [Reaction:1112604] Phosphorylated STATs are released [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1214159] Rose-John, S, 2011-02-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1225065] R-HSA-1112587.4
summation	[Summation:1112551] In untreated cells STAT1 and STAT3 are distributed diffusely...
(hasEvent)	[Pathway:1059683] Interleukin-6 signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781590] Update Tracker - [BlackBoxEvent:1112587] STAT1 and STAT3 dimers translocate to the nucleus - v60:[modifyText]
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