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Details on Person PIP3 dephosphorylated to PIP2 by DPTEN

Class:Id	Reaction:110459
_displayName	PIP3 dephosphorylated to PIP2 by DPTEN
_doRelease	TRUE
_timestamp	2017-08-10 20:45:38
authored	[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
catalystActivity	[CatalystActivity:110458] phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity of DPTEN [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
edited	[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
goBiologicalProcess	[GO_BiologicalProcess:1293] phosphatidylinositol dephosphorylation
input	[SimpleEntity:38117] PIP3 [plasma membrane]
literatureReference	[LiteratureReference:110460] The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels.
modified	[InstanceEdit:143496] Jassal, B, 2004-11-11 14:23:17 [InstanceEdit:164664] Jassal, B, 2005-06-14 12:46:51 [InstanceEdit:169825] Jassal, B, 2005-12-08 15:49:08 [InstanceEdit:170647] Jassal, B, 2006-01-09 10:49:39 [InstanceEdit:2851311] Jupe, S, 2012-12-13 [InstanceEdit:5252137] D'Eustachio, Peter, 2014-02-05 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9015676] D'Eustachio, Peter, 2017-08-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PIP3 dephosphorylated to PIP2 by DPTEN
output	[SimpleEntity:179856] PI(4,5)P2 [plasma membrane] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:110453] Phosphorylation of PIP2 to PIP3 by Dp110 [Drosophila melanogaster] [Reaction:110446] Phospho-Chico: Activated DINR binds p60:Dp110 [Drosophila melanogaster] [Reaction:110459] PIP3 dephosphorylated to PIP2 by DPTEN [Drosophila melanogaster]
releaseDate	2016-01-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8887067] R-DME-110459.2
summation	[Summation:110461] DPTEN (a phosphoinositide phosphatase) catalyses the reversa...
(hasEvent)	[Pathway:110478] Insulin signaling pathway [Drosophila melanogaster]
(inferredFrom)	[Reaction:112095] DAF-18 mediated dephosphorylation of PIP3 to PIP2 [Caenorhabditis elegans]
(precedingEvent)	[Reaction:110453] Phosphorylation of PIP2 to PIP3 by Dp110 [Drosophila melanogaster]
(updatedInstance)	[_UpdateTracker:9787937] Update Tracker - [Reaction:110459] PIP3 dephosphorylated to PIP2 by DPTEN - v44:[add_removeOutput]
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No pathways have been reviewed or authored by PIP3 dephosphorylated to PIP2 by DPTEN (110459)