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Details on Person Phosphorylation of PIP2 to PIP3 by Dp110

Class:IdReaction:110453
_displayNamePhosphorylation of PIP2 to PIP3 by Dp110
_doReleaseTRUE
_timestamp2017-08-10 20:45:40
authored[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
catalystActivity[CatalystActivity:110449] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of p60:Dp110:Phospho-Chico:Activated DINR complex [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
edited[InstanceEdit:111280] Jassal, B, 2004-02-11 10:27:31
goBiologicalProcess[GO_BiologicalProcess:1281] phosphatidylinositol phosphate biosynthetic process
input[SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:110454] The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:143496] Jassal, B, 2004-11-11 14:23:17
[InstanceEdit:164664] Jassal, B, 2005-06-14 12:46:51
[InstanceEdit:164720] Jassal, Bijay, 2005-06-16
[InstanceEdit:164800] Jassal, B, 2005-06-23 08:22:11
[InstanceEdit:164881] Jassal, B, 2005-07-12 08:33:19
[InstanceEdit:169825] Jassal, B, 2005-12-08 15:49:08
[InstanceEdit:170647] Jassal, B, 2006-01-09 10:49:39
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:2851311] Jupe, S, 2012-12-13
[InstanceEdit:5252137] D'Eustachio, Peter, 2014-02-05
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9015676] D'Eustachio, Peter, 2017-08-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylation of PIP2 to PIP3 by Dp110
output[SimpleEntity:38117] PIP3 [plasma membrane]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2016-01-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:56210] Drosophila melanogaster
stableIdentifier[StableIdentifier:8887742] R-DME-110453.2
summation[Summation:110455] PI3Ks are implicated in cell growth, number and size. Dp110,...
(hasEvent)[Pathway:110478] Insulin signaling pathway [Drosophila melanogaster]
(inferredFrom)[Reaction:112090] AGE-1 mediated phosphorylation of PIP2 to PIP3 [Caenorhabditis elegans]
(precedingEvent)[Reaction:110459] PIP3 dephosphorylated to PIP2 by DPTEN [Drosophila melanogaster]
[Reaction:110463] Increased PIP3 levels recruit DAkt1 to the membrane [Drosophila melanogaster]
(updatedInstance)[_UpdateTracker:9787658] Update Tracker - [Reaction:110453] Phosphorylation of PIP2 to PIP3 by Dp110 - v44:[add_removeInput]
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No pathways have been reviewed or authored by Phosphorylation of PIP2 to PIP3 by Dp110 (110453)