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Details on Person LIG1 binds APEX1 and PCNA at SSB
Class:Id Reaction:110371
_displayName LIG1 binds APEX1 and PCNA at SSB
_doRelease TRUE
_timestamp 2016-09-23 16:26:24
authored [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
edited [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input [EntityWithAccessionedSequence:53787] LIG1 [nucleoplasm] [Homo sapiens] [Complex:5651804] APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:5651905] Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair [LiteratureReference:5651903] Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair [LiteratureReference:69178] Interaction between PCNA and DNA ligase I is critical for joinin gof Okazaki fragments and long-patch base-excision repair. [LiteratureReference:5651898] DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories
modified [InstanceEdit:110398] Matthews, L, 2004-02-01 16:00:00 [InstanceEdit:110406] Matthews, L, 2004-04-02 03:43:20 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24 [InstanceEdit:5651906] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:8940146] D'Eustachio, Peter, 2016-09-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name LIG1 binds APEX1 and PCNA at SSB Interaction of APE1 with DNA ligase I
output [Complex:5651808] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2004-03-06
reviewed [InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:5651802] Orlic-Milacic, Marija, 2014-11-24
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:358803] R-HSA-110371.3
summation [Summation:178905] LIG1 (DNA ligase I) is recruited to the long-patch base exci...
(hasEvent) [Pathway:5651801] PCNA-Dependent Long Patch Base Excision Repair [Homo sapiens]
(precedingEvent) [Reaction:5651805] LIG1 bound to APEX1 and PCNA ligates SSB [Homo sapiens]
(updatedInstance) [_UpdateTracker:9782143] Update Tracker - [Reaction:110371] LIG1 binds APEX1 and PCNA at SSB - v59:[add_removeLiteratureReference] [_UpdateTracker:9785435] Update Tracker - [Reaction:110371] LIG1 binds APEX1 and PCNA at SSB - v52:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
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