Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person LIG1 binds APEX1 and PCNA at SSB

Class:IdReaction:110371
_displayNameLIG1 binds APEX1 and PCNA at SSB
_doReleaseTRUE
_timestamp2016-09-23 16:26:24
authored[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
edited[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input[EntityWithAccessionedSequence:53787] LIG1 [nucleoplasm] [Homo sapiens]
[Complex:5651804] APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5651905] Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair
[LiteratureReference:5651903] Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair
[LiteratureReference:69178] Interaction between PCNA and DNA ligase I is critical for joinin gof Okazaki fragments and long-patch base-excision repair.
[LiteratureReference:5651898] DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories
modified[InstanceEdit:110398] Matthews, L, 2004-02-01 16:00:00
[InstanceEdit:110406] Matthews, L, 2004-04-02 03:43:20
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24
[InstanceEdit:5651906] Orlic-Milacic, Marija, 2014-11-25
[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:8940146] D'Eustachio, Peter, 2016-09-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameLIG1 binds APEX1 and PCNA at SSB
Interaction of APE1 with DNA ligase I
output[Complex:5651808] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5651802] Orlic-Milacic, Marija, 2014-11-24
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358803] R-HSA-110371.3
summation[Summation:178905] LIG1 (DNA ligase I) is recruited to the long-patch base exci...
(hasEvent)[Pathway:5651801] PCNA-Dependent Long Patch Base Excision Repair [Homo sapiens]
(precedingEvent)[Reaction:5651805] LIG1 bound to APEX1 and PCNA ligates SSB [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782143] Update Tracker - [Reaction:110371] LIG1 binds APEX1 and PCNA at SSB - v59:[add_removeLiteratureReference]
[_UpdateTracker:9785435] Update Tracker - [Reaction:110371] LIG1 binds APEX1 and PCNA at SSB - v52:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by LIG1 binds APEX1 and PCNA at SSB (110371)