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Details on Person Displacement of MPG glycosylase by APEX1 at the AP site

Class:Id	Reaction:110356
_displayName	Displacement of MPG glycosylase by APEX1 at the AP site
_doRelease	TRUE
_timestamp	2015-02-12 18:21:07
authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[EntityWithAccessionedSequence:50119] APEX1 [nucleoplasm] [Homo sapiens] [Complex:110207] MPG:AP-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:5637618] Human 3-methyladenine-DNA glycosylase: effect of sequence context on excision, association with PCNA, and stimulation by AP endonuclease
modified	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5637644] Orlic-Milacic, Marija, 2014-11-11 [InstanceEdit:5651930] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Displacement of MPG glycosylase by APEX1 at the AP site
output	[EntityWithAccessionedSequence:49155] MPG [nucleoplasm] [Homo sapiens] [Complex:110332] APEX1:AP-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110248] Cleavage of 3-methyladenine by MPG glycosylase [Homo sapiens] [Reaction:110238] MPG glycosylase mediated recognition and binding of 3-methyladenine [Homo sapiens] [Reaction:110250] Cleavage of ethenoadenine by MPG glycosylase [Homo sapiens] [Reaction:110239] MPG glycosylase mediated recognition and binding of ethenoadenine [Homo sapiens] [Reaction:110251] Cleavage of hypoxanthine by MPG glycosylase [Homo sapiens] [Reaction:110240] MPG glycosylase mediated recognition and binding of hypoxanthine [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358442] R-HSA-110356.2
summation	[Summation:178675] APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
(hasEvent)	[Pathway:110357] Displacement of DNA glycosylase by APEX1 [Homo sapiens]
(precedingEvent)	[Reaction:110359] APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785185] Update Tracker - [Reaction:110356] Displacement of MPG glycosylase by APEX1 at the AP site - v52:[modifyText] [_UpdateTracker:9785813] Update Tracker - [Reaction:110356] Displacement of MPG glycosylase by APEX1 at the AP site - v51:[addLiteratureReference, modifyText]
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