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Details on Person LIG3:XRCC1 [nucleoplasm]
Class:Id Complex:110338
_displayName LIG3:XRCC1 [nucleoplasm]
_timestamp 2014-11-20 17:57:12
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
hasComponent
literatureReference [LiteratureReference:111257] Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
modified [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06 [InstanceEdit:186973] Matthews, L, 2006-09-05 23:23:54 [InstanceEdit:5637652] Orlic-Milacic, Marija, 2014-11-11 [InstanceEdit:5649639] Orlic-Milacic, Marija, 2014-11-20
name LIG3:XRCC1
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:367575] R-HSA-110338.1
(hasCandidate) [CandidateSet:9980180] XRCC4:LIG4, (LIG3:XRCC1, LIG1) [nucleoplasm] [Human herpesvirus 8]
(hasComponent) [Complex:110339] LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] [Homo sapiens] [Complex:110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm] [Homo sapiens] [Complex:110343] LIG3:XRCC1:POLB:dsDNA [nucleoplasm] [Homo sapiens] [Complex:5649722] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:dsDNA [nucleoplasm] [Homo sapiens] [Complex:5649729] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA [nucleoplasm] [Homo sapiens] [Complex:5649733] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm] [Homo sapiens] [Complex:5649816] NEIL1,NEIL2:POLB:LIG3:XRCC1:PNKP:SSB-gap-dsDNA [nucleoplasm] [Homo sapiens] [Complex:5687677] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:LIG3:XRCC1 [nucleoplasm] [Homo sapiens] [Complex:9979939] HHV8 linear DNA with extended microhomologous 3'-ssDNA overhangs:MRN:RBBP8:LIG3:XRCC1 [nucleoplasm] [Homo sapiens]
(hasMember) [DefinedSet:5690475] LIG1,LIG3:XRCC1 [nucleoplasm] [Homo sapiens]
(input) [Reaction:110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB [Homo sapiens] [Reaction:5649726] LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [Homo sapiens] [Reaction:5687673] MRN recruits LIG3:XRCC1 to MMEJ sites [Homo sapiens]
(output) [Reaction:110380] Dissociation of LIG3:XRCC1 complex from the BER site [Homo sapiens] [Reaction:5649724] LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site [Homo sapiens] [Reaction:5687675] LIG3 ligates remaining SSBs in MMEJ [Homo sapiens]
(updatedInstance) [_UpdateTracker:9889831] Update Tracker - [Complex:110338] LIG3:XRCC1 [nucleoplasm] - v52:[modifyName]
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Protein identifiers
No pathways have been reviewed or authored by LIG3:XRCC1 [nucleoplasm] (110338)