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Details on Person Insertion of correct bases opposite the lesion by POLH

Class:Id	Reaction:110317
_displayName	Insertion of correct bases opposite the lesion by POLH
_doRelease	TRUE
_timestamp	2015-02-12 19:19:18
authored	[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
catalystActivity	[CatalystActivity:110318] DNA-directed DNA polymerase activity of POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
edited	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input	[Complex:110288] POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] [Homo sapiens] [SimpleEntity:29604] dATP [nucleoplasm] [SimpleEntity:29604] dATP [nucleoplasm]
literatureReference	[LiteratureReference:5653907] Low fidelity DNA synthesis by human DNA polymerase-eta [LiteratureReference:111302] Mechanisms of accurate translesion synthesis by human DNA polymerase eta.
modified	[InstanceEdit:111298] Gopinathrao, G, 2004-02-11 18:33:11 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:167005] Schmidt, EE, 2005-10-10 15:17:32 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5653910] Orlic-Milacic, Marija, 2014-12-02 [InstanceEdit:5654982] Orlic-Milacic, Marija, 2014-12-04 [InstanceEdit:5656193] Orlic-Milacic, Marija, 2014-12-11 [InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5663089] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5663092] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Insertion of correct bases opposite the lesion by POLH
output	[Complex:110290] POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] [Homo sapiens] [SimpleEntity:113541] PPi [nucleoplasm] [SimpleEntity:113541] PPi [nucleoplasm]
precedingEvent	[Reaction:110316] POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template [Homo sapiens] [Reaction:5652009] RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5653898] Orlic-Milacic, Marija, 2014-12-02
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361393] R-HSA-110317.2
summation	[Summation:178902] DNA polymerase eta (POLH) correctly incorporates two adenine...
(hasEvent)	[Pathway:110320] Translesion Synthesis by POLH [Homo sapiens]
(precedingEvent)	[Reaction:110319] Elongation by POLH [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784987] Update Tracker - [Reaction:110317] Insertion of correct bases opposite the lesion by POLH - v52:[addInput, addLiteratureReference, addOutput, modifyText]
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