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Details on Person POLZ extends translesion synthesis

Class:IdReaction:110311
_displayNamePOLZ extends translesion synthesis
_doReleaseTRUE
_timestamp2017-04-26 20:36:37
authored[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
catalystActivity[CatalystActivity:5652145] DNA-directed DNA polymerase activity of POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
edited[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input[Complex:5652152] POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] [Homo sapiens]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
[SimpleEntity:30555] dNTP [nucleoplasm]
literatureReference[LiteratureReference:5652030] Deoxycytidyl transferase activity of yeast REV1 protein
[LiteratureReference:5652168] The role of hRev7, the accessory subunit of hPol?, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE)
[LiteratureReference:5653633] Thymine-thymine dimer bypass by yeast DNA polymerase zeta
[LiteratureReference:5653634] Human Pol ? purified with accessory subunits is active in translesion DNA synthesis and complements Pol ? in cisplatin bypass
[LiteratureReference:5653638] Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
modified[InstanceEdit:111298] Gopinathrao, G, 2004-02-11 18:33:11
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:350785] Gopinathrao, G, 2008-05-20 18:11:14
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:3006723] Jassal, B, 2013-02-01
[InstanceEdit:5652158] Orlic-Milacic, Marija, 2014-11-28
[InstanceEdit:5652162] Orlic-Milacic, Marija, 2014-11-28
[InstanceEdit:5652169] Orlic-Milacic, Marija, 2014-11-28
[InstanceEdit:5653641] Orlic-Milacic, Marija, 2014-12-01
[InstanceEdit:5653642] Orlic-Milacic, Marija, 2014-12-01
[InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663089] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663092] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5676171] Orlic-Milacic, Marija, 2015-02-19
[InstanceEdit:8986403] Orlic-Milacic, Marija, 2017-04-26
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePOLZ extends translesion synthesis
output[Complex:110279] POLZ [nucleoplasm] [Homo sapiens]
[Complex:5652153] REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] [Homo sapiens]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
[SimpleEntity:113541] PPi [nucleoplasm]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359916] R-HSA-110311.3
summation[Summation:178697] After REV1 inserts a nucleotide directly opposite the templa...
(hasEvent)[Pathway:110312] Translesion synthesis by REV1 [Homo sapiens]
(precedingEvent)[Reaction:5653756] TRIM25 binds monoUb:164-PCNA [Homo sapiens]
[Pathway:5656169] Termination of translesion DNA synthesis [Homo sapiens]
(replacementInstances)[_Deleted:5676178] Deletion of instance: 110324
(updatedInstance)[_UpdateTracker:9784868] Update Tracker - [Reaction:110311] POLZ extends translesion synthesis - v52:[addLiteratureReference, add_removeCatalystActivity, add_removeInput, add_removeOutput, modifyText]
[_UpdateTracker:9788021] Update Tracker - [Reaction:110311] POLZ extends translesion synthesis - v44:[add_removeOutput]
[_UpdateTracker:9791880] Update Tracker - [Reaction:110311] POLZ extends translesion synthesis - v25:[add_removeOutput]
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No pathways have been reviewed or authored by POLZ extends translesion synthesis (110311)
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