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Details on Person REV1 inserts dCMP opposite to AP sites in DNA

Class:IdReaction:110308
_displayNameREV1 inserts dCMP opposite to AP sites in DNA
_doReleaseTRUE
_timestamp2015-02-12 19:19:20
authored[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
catalystActivity[CatalystActivity:110309] deoxycytidyl transferase activity of REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
edited[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input[Complex:110283] REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] [Homo sapiens]
[SimpleEntity:30185] dCTP [nucleoplasm]
literatureReference[LiteratureReference:111301] The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.
[LiteratureReference:111303] The human REV1 gene codes for a DNA template-dependent dCMP transferase.
[LiteratureReference:5652030] Deoxycytidyl transferase activity of yeast REV1 protein
[LiteratureReference:5644000] Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion
modified[InstanceEdit:111298] Gopinathrao, G, 2004-02-11 18:33:11
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5644017] Orlic-Milacic, Marija, 2014-11-19
[InstanceEdit:5652048] Orlic-Milacic, Marija, 2014-11-26
[InstanceEdit:5652080] Orlic-Milacic, Marija, 2014-11-26
[InstanceEdit:5663042] Orlic-Milacic, Marija, 2015-01-14
[InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663089] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663092] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameREV1 inserts dCMP opposite to AP sites in DNA
output[Complex:110285] REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358861] R-HSA-110308.2
summation[Summation:178952] REV1 acts as a deoxycytidyl transferase to incorporate a sin...
(hasEvent)[Pathway:110312] Translesion synthesis by REV1 [Homo sapiens]
(precedingEvent)[Reaction:5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785460] Update Tracker - [Reaction:110308] REV1 inserts dCMP opposite to AP sites in DNA - v52:[addInput, addLiteratureReference, modifyText]
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