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Details on Person REV1 binds AP-dsDNA

Class:IdReaction:110307
_displayNameREV1 binds AP-dsDNA
_doReleaseTRUE
_timestamp2015-02-12 19:19:20
authored[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32
edited[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input[EntityWithAccessionedSequence:3006726] REV1 [nucleoplasm] [Homo sapiens]
[Complex:5652039] MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:111301] The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.
[LiteratureReference:111303] The human REV1 gene codes for a DNA template-dependent dCMP transferase.
[LiteratureReference:5652041] A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage
[LiteratureReference:5652047] Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1
modified[InstanceEdit:111298] Gopinathrao, G, 2004-02-11 18:33:11
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:350785] Gopinathrao, G, 2008-05-20 18:11:14
[InstanceEdit:2671732] D'Eustachio, P, 2012-11-23
[InstanceEdit:3006723] Jassal, B, 2013-02-01
[InstanceEdit:5644004] Orlic-Milacic, Marija, 2014-11-19
[InstanceEdit:5652048] Orlic-Milacic, Marija, 2014-11-26
[InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663089] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663091] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663092] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameREV1 binds AP-dsDNA
output[Complex:110283] REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5652011] Orlic-Milacic, Marija, 2014-11-26
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358657] R-HSA-110307.2
summation[Summation:178513] REV1 is a deoxycytidyl transferase that belongs to the DNA p...
(hasEvent)[Pathway:110312] Translesion synthesis by REV1 [Homo sapiens]
(precedingEvent)[Reaction:110308] REV1 inserts dCMP opposite to AP sites in DNA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785496] Update Tracker - [Reaction:110307] REV1 binds AP-dsDNA - v52:[addLiteratureReference, add_removeInput, modifyText]
[_UpdateTracker:9787967] Update Tracker - [Reaction:110307] REV1 binds AP-dsDNA - v44:[add_removeInput]
[_UpdateTracker:9791884] Update Tracker - [Reaction:110307] REV1 binds AP-dsDNA - v25:[add_removeInput]
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