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Details on Person Cleavage of 3-methyladenine by MPG glycosylase

Class:IdReaction:110248
_displayNameCleavage of 3-methyladenine by MPG glycosylase
_doReleaseTRUE
_timestamp2015-02-12 18:21:04
authored[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
catalystActivity[CatalystActivity:5649472] DNA N-glycosylase activity of MPG:3meA-dsDNA [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input[Complex:110202] MPG:3meA-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5634865] Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16
[LiteratureReference:5634867] Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere
[LiteratureReference:5634848] Purification and characterization of human 3-methyladenine-DNA glycosylase
[LiteratureReference:5634869] Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision
[LiteratureReference:5634882] Release of normal bases from intact DNA by a native DNA repair enzyme
modified[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
[InstanceEdit:111239] Matthews, L, 2004-02-09 03:00:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671733] D'Eustachio, P, 2012-11-23
[InstanceEdit:5634881] Orlic-Milacic, Marija, 2014-11-06
[InstanceEdit:5634887] Orlic-Milacic, Marija, 2014-11-06
[InstanceEdit:5649480] Orlic-Milacic, Marija, 2014-11-20
[InstanceEdit:5658589] Orlic-Milacic, Marija, 2014-12-19
[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCleavage of 3-methyladenine by MPG glycosylase
output[SimpleEntity:30947] MADE [nucleoplasm]
[Complex:110207] MPG:AP-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358814] R-HSA-110248.2
summation[Summation:178539] MPG, a 3-methyladenine DNA glycosylase, removes the alkylate...
(hasEvent)[Pathway:110331] Cleavage of the damaged purine [Homo sapiens]
(precedingEvent)[Reaction:110356] Displacement of MPG glycosylase by APEX1 at the AP site [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784925] Update Tracker - [Reaction:110248] Cleavage of 3-methyladenine by MPG glycosylase - v52:[add_removeCatalystActivity, removeLiteratureReference]
[_UpdateTracker:9785704] Update Tracker - [Reaction:110248] Cleavage of 3-methyladenine by MPG glycosylase - v51:[addLiteratureReference, modifyText]
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