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Details on Person MPG glycosylase mediated recognition and binding of ethenoadenine

Class:IdReaction:110239
_displayNameMPG glycosylase mediated recognition and binding of ethenoadenine
_doReleaseTRUE
_timestamp2015-02-12 18:21:09
authored[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input[EntityWithAccessionedSequence:49155] MPG [nucleoplasm] [Homo sapiens]
[GenomeEncodedEntity:110203] EtAD-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5634850] 1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase)
[LiteratureReference:5634851] Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA
modified[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5634875] Orlic-Milacic, Marija, 2014-11-06
[InstanceEdit:5673691] Orlic-Milacic, Marija, 2015-02-09
[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMPG glycosylase mediated recognition and binding of ethenoadenine
output[Complex:110204] MPG:EtAD-dsDNA [nucleoplasm] [Homo sapiens]
releaseDate2004-03-06
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361151] R-HSA-110239.2
summation[Summation:178954] MPG, a 3-methyladenine DNA glycosylase, recognizes alkylatio...
(hasEvent)[Pathway:110330] Recognition and association of DNA glycosylase with site containing an affected purine [Homo sapiens]
(precedingEvent)[Reaction:110250] Cleavage of ethenoadenine by MPG glycosylase [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785888] Update Tracker - [Reaction:110239] MPG glycosylase mediated recognition and binding of ethenoadenine - v51:[addLiteratureReference, modifyText]
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