Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine

Class:IdReaction:110237
_displayNameMUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine
_doReleaseTRUE
_timestamp2018-06-29 14:36:37
authored[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input[GenomeEncodedEntity:110198] (8oxoG:Ade)-dsDNA [nucleoplasm] [Homo sapiens]
[DefinedSet:9606670] MUTYH [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5635944] Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage
[LiteratureReference:5635925] Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria
[LiteratureReference:5635939] hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs
modified[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5635945] Orlic-Milacic, Marija, 2014-11-07
[InstanceEdit:5635948] Orlic-Milacic, Marija, 2014-11-07
[InstanceEdit:5659709] Orlic-Milacic, Marija, 2014-12-22
[InstanceEdit:5673691] Orlic-Milacic, Marija, 2015-02-09
[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9606673] Orlic-Milacic, Marija, 2018-04-24
[InstanceEdit:9612702] Orlic-Milacic, Marija, 2018-06-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine
output[Complex:110199] MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm] [Homo sapiens]
releaseDate2004-03-06
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
[InstanceEdit:9612701] Nakabeppu, Yusaku, 2018-06-28
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360005] R-HSA-110237.4
summation[Summation:178957] MUTYH (MYH), an adenine DNA glycosylase, was cloned as the h...
(hasEvent)[Pathway:110330] Recognition and association of DNA glycosylase with site containing an affected purine [Homo sapiens]
(normalReaction)[FailedReaction:9608288] Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine [Homo sapiens]
(precedingEvent)[Reaction:110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779198] Update Tracker - [Reaction:110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - v66:[modifyText]
[_UpdateTracker:9779312] Update Tracker - [Reaction:110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - v65:[add_removeInput]
[_UpdateTracker:9785045] Update Tracker - [Reaction:110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - v52:[modifyText]
[_UpdateTracker:9785703] Update Tracker - [Reaction:110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - v51:[addLiteratureReference, modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine (110237)
Follow Reactome