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Details on Person OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine

Class:IdReaction:110235
_displayNameOGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine
_doReleaseTRUE
_timestamp2019-10-10 15:37:43
authored[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
[InstanceEdit:9663704] Orlic-Milacic, Marija, 2019-10-10
input[EntityWithAccessionedSequence:60887] OGG1 [nucleoplasm] [Homo sapiens]
[GenomeEncodedEntity:110184] (8oxoG:Cyt)-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5635989] Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue
[LiteratureReference:5635981] Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase
[LiteratureReference:5635964] Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
[LiteratureReference:5635990] Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
[LiteratureReference:5635965] Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
[LiteratureReference:5635975] Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
modified[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5636004] Orlic-Milacic, Marija, 2014-11-08
[InstanceEdit:5651910] Orlic-Milacic, Marija, 2014-11-25
[InstanceEdit:5659711] Orlic-Milacic, Marija, 2014-12-22
[InstanceEdit:5673691] Orlic-Milacic, Marija, 2015-02-09
[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9656951] Orlic-Milacic, Marija, 2019-08-06
[InstanceEdit:9663709] Orlic-Milacic, Marija, 2019-10-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameOGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine
output[Complex:110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
[InstanceEdit:9663702] Vlahopoulos, Spiros, 2019-10-02
[InstanceEdit:9663703] Boldogh, Istvan, 2019-10-08
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359598] R-HSA-110235.4
summation[Summation:178869] OGG1 is an N-glycosylase and DNA lyase that recognizes oxida...
(hasEvent)[Pathway:110330] Recognition and association of DNA glycosylase with site containing an affected purine [Homo sapiens]
(normalReaction)[FailedReaction:9656254] Defective OGG1 mutants show decreased binding to 8-oxoguanine [Homo sapiens]
(precedingEvent)[Reaction:110243] Excision of 8-oxoguanine by OGG1 glycosylase [Homo sapiens]
(updatedInstance)[_UpdateTracker:9777418] Update Tracker - [Reaction:110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine - v71:[modifyText]
[_UpdateTracker:9785788] Update Tracker - [Reaction:110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine - v51:[addLiteratureReference, modifyText]
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