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Details on Person Cleavage of ethenocytosine by TDG glycosylase

Class:Id	Reaction:110234
_displayName	Cleavage of ethenocytosine by TDG glycosylase
_doRelease	TRUE
_timestamp	2015-02-12 18:21:05
authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
catalystActivity	[CatalystActivity:5649470] DNA N-glycosylase activity of TDG:EtCYT-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[Complex:110190] TDG:EtCYT-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:5637507] A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch
modified	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671733] D'Eustachio, P, 2012-11-23 [InstanceEdit:5637511] Orlic-Milacic, Marija, 2014-11-10 [InstanceEdit:5649480] Orlic-Milacic, Marija, 2014-11-20 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cleavage of ethenocytosine by TDG glycosylase
output	[SimpleEntity:110233] EtCYT [nucleoplasm] [Complex:110191] TDG:AP-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110210] TDG glycosylase mediated recognition and binding of an ethenocytosine [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360746] R-HSA-110234.2
summation	[Summation:178545] TDG, a G/T mismatch-specific DNA glycosylase, cleaves etheno...
(hasEvent)	[Pathway:110329] Cleavage of the damaged pyrimidine [Homo sapiens]
(precedingEvent)	[Reaction:110350] Displacement of TDG glycosylase by APEX1 at the AP site [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784898] Update Tracker - [Reaction:110234] Cleavage of ethenocytosine by TDG glycosylase - v52:[add_removeCatalystActivity, modifyText] [_UpdateTracker:9785878] Update Tracker - [Reaction:110234] Cleavage of ethenocytosine by TDG glycosylase - v51:[addLiteratureReference, modifyText]
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