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Details on Person Cleavage of uracil by SMUG1 glycosylase
Class:Id Reaction:110221
_displayName Cleavage of uracil by SMUG1 glycosylase
_doRelease TRUE
_timestamp 2015-02-12 18:21:06
authored [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
catalystActivity [CatalystActivity:5649471] single-strand selective uracil DNA N-glycosylase activity of SMUG1:Ura-DNA [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input [Complex:110163] SMUG1:Ura-DNA [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:5637522] Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors [LiteratureReference:5637520] Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions
modified [InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00 [InstanceEdit:111239] Matthews, L, 2004-02-09 03:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5637526] Orlic-Milacic, Marija, 2014-11-10 [InstanceEdit:5649480] Orlic-Milacic, Marija, 2014-11-20 [InstanceEdit:5651910] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5658605] Orlic-Milacic, Marija, 2014-12-19 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Cleavage of uracil by SMUG1 glycosylase
output [SimpleEntity:29554] Ura [nucleoplasm] [Complex:110192] SMUG1:AP-DNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2004-03-06
reviewed [InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360859] R-HSA-110221.2
summation [Summation:178552] SMUG1 is a single-strand selective monofunctional uracil DNA...
(hasEvent) [Pathway:110329] Cleavage of the damaged pyrimidine [Homo sapiens]
(precedingEvent) [Reaction:110351] Displacement of SMUG1 glycosylase by APEX1 at the AP site [Homo sapiens]
(updatedInstance) [_UpdateTracker:9785483] Update Tracker - [Reaction:110221] Cleavage of uracil by SMUG1 glycosylase - v52:[add_removeCatalystActivity, modifyText, removeLiteratureReference] [_UpdateTracker:9785930] Update Tracker - [Reaction:110221] Cleavage of uracil by SMUG1 glycosylase - v51:[addLiteratureReference, modifyText]
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