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Details on Person Cleavage of uracil by UNG glycosylase

Class:Id	Reaction:110215
_displayName	Cleavage of uracil by UNG glycosylase
_doRelease	TRUE
_timestamp	2015-02-12 18:21:06
authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
catalystActivity	[CatalystActivity:5649475] uracil DNA N-glycosylase activity of UNG-1:(Ura:Gua)-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[Complex:110152] UNG-1:(Ura:Gua)-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:111242] Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
modified	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00 [InstanceEdit:111239] Matthews, L, 2004-02-09 03:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5634879] Orlic-Milacic, Marija, 2014-11-06 [InstanceEdit:5635916] Orlic-Milacic, Marija, 2014-11-07 [InstanceEdit:5649480] Orlic-Milacic, Marija, 2014-11-20 [InstanceEdit:5658593] Orlic-Milacic, Marija, 2014-12-19 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674537] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cleavage of uracil by UNG glycosylase
output	[SimpleEntity:29554] Ura [nucleoplasm] [Complex:110188] UNG-1:AP-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110156] UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361164] R-HSA-110215.2
summation	[Summation:178555] UNG, a DNA uracil glycosylase, excises the uracil base gener...
(hasEvent)	[Pathway:110329] Cleavage of the damaged pyrimidine [Homo sapiens]
(precedingEvent)	[Reaction:110349] Displacement of UNG glycosylase by APEX1 at the AP site [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785253] Update Tracker - [Reaction:110215] Cleavage of uracil by UNG glycosylase - v52:[add_removeCatalystActivity, modifyText, removeLiteratureReference] [_UpdateTracker:9785688] Update Tracker - [Reaction:110215] Cleavage of uracil by UNG glycosylase - v51:[add_removeLiteratureReference, modifyText]
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