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Details on Person ADP + ADP <=> AMP + ATP [AK2]

Class:IdReaction:110144
_displayNameADP + ADP <=> AMP + ATP [AK2]
_doReleaseTRUE
_timestamp2025-12-02 23:58:45
catalystActivity[CatalystActivity:110089] AMP kinase activity of AK2 [mitochondrial intermembrane space]
catalystActivityReference[CatalystActivityReference:9643852] adenylate kinase activity of AK2 [mitochondrial intermembrane space] Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne muscular dystrophic serum aberrant adenylate kinase
compartment[Compartment:70101] cytosol
[Compartment:17927] mitochondrial intermembrane space
created[InstanceEdit:110076] D'Eustachio, P, 2004-01-28 17:55:00
crossReference[DatabaseIdentifier:9975775] RHEA:12975
input[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
literatureReference[LiteratureReference:110124] Rat liver adenosine triphosphate:adenosine monophosphate phosphotransferase activity. II. Subcellular localization of adenylate kinase isozymes
[LiteratureReference:110081] Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne muscular dystrophic serum aberrant adenylate kinase
modified[InstanceEdit:110253] D'Eustachio, P, 0000-00-00 00:00:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:500083] D'Eustachio, P, 2010-01-30
[InstanceEdit:504063] D'Eustachio, P, 2010-02-05
[InstanceEdit:504071] D'Eustachio, P, 2010-02-07
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9975767] D'Eustachio, Peter, 2025-12-02
nameADP + ADP <=> AMP + ATP [AK2]
2 ADP => AMP + ATP
output[SimpleEntity:76577] AMP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
releaseDate2004-07-06
reverseReaction
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359223] R-HSA-110144.6
summation[Summation:178390] Mitochondrial adenylate kinase 2 (AK2) catalyzes the reactio...
(hasEvent)[Pathway:499943] Interconversion of nucleotide di- and triphosphates [Homo sapiens]
(replacementInstances)[_Deleted:500085] Deletion of instance: 110131
(reverseReaction)[Reaction:110145] AMP + ATP <=> ADP + ADP [AK2] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790128] Update Tracker - [Reaction:110144] ADP + ADP <=> AMP + ATP [AK2] - v35:[modifyText]
[_UpdateTracker:9790953] Update Tracker - [Reaction:110144] ADP + ADP <=> AMP + ATP [AK2] - v32:[addLiteratureReference, modifyText]
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