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Details on Person (d)GDP + ADP <=> (d)GMP + ATP (GUK1)
Class:Id Reaction:110133
_displayName (d)GDP + ADP <=> (d)GMP + ATP (GUK1)
_doRelease TRUE
_timestamp 2025-12-04 01:21:30
catalystActivity [CatalystActivity:74189] GMP kinase activity of GUK1 [cytosol]
catalystActivityReference [CatalystActivityReference:9643996] guanylate kinase activity of GUK1 [cytosol] Cloning, characterization, and modeling of mouse and human guanylate kinases
compartment [Compartment:70101] cytosol
created [InstanceEdit:110076] D'Eustachio, P, 2004-01-28 17:55:00
crossReference [DatabaseIdentifier:9975907] RHEA:20782 [DatabaseIdentifier:9975912] RHEA:12699
input [DefinedSet:500077] (d)GDP [cytosol] [SimpleEntity:29370] ADP [cytosol]
literatureReference [LiteratureReference:110117] Guanylate kinases from human erythrocytes, hog brain, and rat liver [LiteratureReference:500070] Cloning, characterization, and modeling of mouse and human guanylate kinases [LiteratureReference:110100] Studies on the properties and tissue distribution of the isozymes of guanylate kinase in man [LiteratureReference:110121] Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
modified [InstanceEdit:110253] D'Eustachio, P, 0000-00-00 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:500076] D'Eustachio, P, 2010-01-30 [InstanceEdit:504063] D'Eustachio, P, 2010-02-05 [InstanceEdit:504071] D'Eustachio, P, 2010-02-07 [InstanceEdit:504072] D'Eustachio, P, 2010-02-07 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8956390] D'Eustachio, Peter, 2017-01-22 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9975916] D'Eustachio, Peter, 2025-12-04
name (d)GDP + ADP <=> (d)GMP + ATP (GUK1) GDP + ADP => GMP + ATP dGDP + ADP => dGMP + ATP
output [DefinedSet:500071] (d)GMP [cytosol] [SimpleEntity:113592] ATP [cytosol]
releaseDate 2004-07-06
reverseReaction
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:504064] D'Eustachio, P, 2010-02-05
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:359750] R-HSA-110133.7
summation [Summation:500078] Cytosolic guanylate kinase 1 (GUK1) catalyzes the reversible...
(hasEvent) [Pathway:499943] Interconversion of nucleotide di- and triphosphates [Homo sapiens]
(replacementInstances) [_Deleted:500079] Deletion of instance: 110134 [_Deleted:500081] Deletion of instance: 110116
(reverseReaction) [Reaction:73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1) [Homo sapiens]
(updatedInstance) [_UpdateTracker:9791062] Update Tracker - [Reaction:110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - v32:[addLiteratureReference, add_removeInput, add_removeOutput, add_removeSummation]
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