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Details on Person MAP2K2 phosphorylates MAPK1

Class:IdReaction:109862
_displayNameMAP2K2 phosphorylates MAPK1
_doReleaseTRUE
_timestamp2015-03-20 14:47:03
authored[InstanceEdit:158672] Charalambous, M, 2005-02-04 06:50:22
catalystActivity[CatalystActivity:109861] protein serine/threonine kinase activity of p-S,T-MAP2K2:MAPK1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:112400] Charalambous, M, 2004-04-29 09:21:24
edited[InstanceEdit:165100] Schmidt, EE, 0000-00-00 00:00:00
figure[Figure:158670] /figures/MEK_P_ERK.jpg
input[Complex:109849] p-S,T-MAP2K2:MAPK1 [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:110054] Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
[LiteratureReference:5673960] MEK1/2 dual-specificity protein kinases: structure and regulation
modified[InstanceEdit:110001] Schmidt, EE, 2004-01-23 05:11:12
[InstanceEdit:112335] Schmidt, EE, 2004-04-27 10:09:34
[InstanceEdit:112397] Schmidt, EE, 2004-04-29 09:21:20
[InstanceEdit:158660] Schmidt, EE, 2005-02-04 11:34:53
[InstanceEdit:163616] Schmidt, EE, 2005-05-03 09:53:07
[InstanceEdit:188337] Jassal, Bijay, 2006-10-10
[InstanceEdit:188624] Jassal, Bijay, 2006-10-19
[InstanceEdit:196906] Gopinathrao, G, 2007-04-25 14:54:44
[InstanceEdit:266142] Jassal, B, 2008-04-25 09:33:55
[InstanceEdit:266143] Jassal, B, 2008-04-25 09:43:23
[InstanceEdit:1008271] Shamovsky, V, 2010-11-10
[InstanceEdit:5684284] Shamovsky, Veronica, 2015-03-20
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMAP2K2 phosphorylates MAPK1
output[Complex:109854] p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2010-12-14
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360846] R-HSA-109862.2
summation[Summation:158666] MAP2K2 (MEK2) phosphorylates MAPK1 (ERK2). Phosphorylation o...
(hasEvent)[Pathway:112411] MAPK1 (ERK2) activation [Homo sapiens]
[Pathway:445144] Signal transduction by L1 [Homo sapiens]
(inferredFrom)[Reaction:451516] activated MEK2 phosphorylates ERK2 [Gallus gallus]
(precedingEvent)[Reaction:109864] Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784631] Update Tracker - [Reaction:109862] MAP2K2 phosphorylates MAPK1 - v53:[addLiteratureReference, modifyText]
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