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Details on Person MAP2K1 binds MAPK3

Class:IdReaction:109857
_displayNameMAP2K1 binds MAPK3
_doReleaseTRUE
_timestamp2015-03-20 14:46:29
authored[InstanceEdit:158672] Charalambous, M, 2005-02-04 06:50:22
compartment[Compartment:70101] cytosol
created[InstanceEdit:112400] Charalambous, M, 2004-04-29 09:21:24
edited[InstanceEdit:165100] Schmidt, EE, 0000-00-00 00:00:00
figure[Figure:158658] /figures/MEK_ERK.jpg
input[EntityWithAccessionedSequence:109837] p-S218,S222-MAP2K1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:59284] MAPK3 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:110054] Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
modified[InstanceEdit:110001] Schmidt, EE, 2004-01-23 05:11:12
[InstanceEdit:112397] Schmidt, EE, 2004-04-29 09:21:20
[InstanceEdit:158660] Schmidt, EE, 2005-02-04 11:34:53
[InstanceEdit:163616] Schmidt, EE, 2005-05-03 09:53:07
[InstanceEdit:188337] Jassal, Bijay, 2006-10-10
[InstanceEdit:188624] Jassal, Bijay, 2006-10-19
[InstanceEdit:196906] Gopinathrao, G, 2007-04-25 14:54:44
[InstanceEdit:266142] Jassal, B, 2008-04-25 09:33:55
[InstanceEdit:266143] Jassal, B, 2008-04-25 09:43:23
[InstanceEdit:451698] Jupe, S, 2010-01-08
[InstanceEdit:1008271] Shamovsky, V, 2010-11-10
[InstanceEdit:5684280] Shamovsky, Veronica, 2015-03-20
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMAP2K1 binds MAPK3
output[Complex:109838] p-2S-MAP2K1:MAPK3 [cytosol] [Homo sapiens]
precedingEvent
regulatedBy[PositiveRegulation:1112768] Positive regulation by 'IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane]'
releaseDate2010-12-14
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361940] R-HSA-109857.4
summation[Summation:158669] In the cytoplasm phosphorylated MAP2K1 (MEK1) may encounter ...
[Summation:1112772] IL-6-type receptor activation leads to induction of the MAPK...
(hasEvent)[Pathway:110056] MAPK3 (ERK1) activation [Homo sapiens]
(precedingEvent)[Reaction:109860] MAP2K1 phosphorylates MAPK3 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775717] Update Tracker - [Reaction:109857] MAP2K1 binds MAPK3 - v78:[addSummation]
[_UpdateTracker:9784557] Update Tracker - [Reaction:109857] MAP2K1 binds MAPK3 - v53:[modifyText]
[_UpdateTracker:9785952] Update Tracker - [Reaction:109857] MAP2K1 binds MAPK3 - v50:[addRegulator]
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