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Details on Person p21 RAS:GDP [plasma membrane]

Class:IdComplex:109796
_displayNamep21 RAS:GDP [plasma membrane]
_timestamp2019-08-12 14:51:19
compartment[Compartment:876] plasma membrane
created[InstanceEdit:109781] Schmidt, EE, 2004-01-21 04:32:59
hasComponent
modified[InstanceEdit:1998741] Orlic-Milacic, Marija, 2011-11-19
[InstanceEdit:2213009] Matthews, L, 2012-04-27
[InstanceEdit:9658203] Rothfels, Karen, 2019-08-12
namep21 RAS:GDP
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:365781] R-HSA-109796.2
(hasComponent)[Complex:9632908] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] [Homo sapiens]
(input)[Reaction:109807] GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS [Homo sapiens]
[Reaction:109817] GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS [Homo sapiens]
[Reaction:109825] (Controversial - not included in public release.) SOS mediated nucleotide exchange of RAS (IRS, Crk) [Homo sapiens]
[Reaction:167216] SOS-mediated nucleotide exchange on Ras, activating it [Homo sapiens]
[Reaction:177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) [Homo sapiens]
[Reaction:177945] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) [Homo sapiens]
[Reaction:186834] SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) [Homo sapiens]
[Reaction:210977] Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) [Homo sapiens]
[Reaction:354152] AlphaIIbbeta3 mediated nucleotide exchange of RAS (SHC) [Homo sapiens]
[Reaction:392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras [Homo sapiens]
List all 68 refering instances
(normalEntity)[EntityFunctionalStatus:9649745] gain_of_function of RAS GEF mutants:GDP [plasma membrane]
(output)[Reaction:5658231] RAS GAPs stimulate RAS GTPase activity [Homo sapiens]
[Reaction:8981353] RASA1 stimulates RAS GTPase activity [Homo sapiens]
[Reaction:9649733] mature p21 RAS binds GDP [Homo sapiens]
[Reaction:9649736] RAS intrinsic GTPase activity hydrolyzes GTP to GDP [Homo sapiens]
(updatedInstance)[_UpdateTracker:9870932] Update Tracker - [Complex:109796] p21 RAS:GDP [plasma membrane] - v39:[addCompartment]
[_UpdateTracker:9871887] Update Tracker - [Complex:109796] p21 RAS:GDP [plasma membrane] - v41:[removeCompartment]
[_UpdateTracker:9892515] Update Tracker - [Complex:109796] p21 RAS:GDP [plasma membrane] - v53:[updateContainedComponent]
[_UpdateTracker:9900875] Update Tracker - [Complex:109796] p21 RAS:GDP [plasma membrane] - v70:[add_removeHasComponent]
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No pathways have been reviewed or authored by p21 RAS:GDP [plasma membrane] (109796)
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