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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person p-S259,S621-RAF1 [cytosol]

Class:IdEntityWithAccessionedSequence:109786
_displayNamep-S259,S621-RAF1 [cytosol]
_timestamp2013-05-03 18:44:30
compartment[Compartment:70101] cytosol
created[InstanceEdit:109781] Schmidt, EE, 2004-01-21 04:32:59
endCoordinate648
hasModifiedResidue[ModifiedResidue:109784] O-phospho-L-serine at 259
[ModifiedResidue:109785] O-phospho-L-serine at 621
modified[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08
[InstanceEdit:443438] Jupe, S, 2009-10-06
[InstanceEdit:443445] Jupe, S, 2009-10-06
[InstanceEdit:3009422] Jassal, B, 2013-02-05
[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:3448660] Wu, G, 2013-05-16
namep-S259,S621-RAF1
RAF proto-oncogene serine/threonine-protein kinase
Raf-1
C-RAF
cRaf
referenceEntity[ReferenceGeneProduct:58255] UniProt:P04049 RAF1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:370638] R-HSA-109786.1
startCoordinate1
(hasComponent)[Complex:109787] p-S259,S621-RAF1:YWHAB [cytosol] [Homo sapiens]
[Complex:109788] RAS:RAF [plasma membrane] [Homo sapiens]
[Complex:206716] RAS:GTP:p-S259,S621-RAF1 [plasma membrane] [Homo sapiens]
[Complex:206726] p-RAF1:Ras:GTP [plasma membrane] [Homo sapiens]
[Complex:206920] p-RAF1:14-3-3zeta [cytosol] [Homo sapiens]
(hasMember)[DefinedSet:5672708] inactive RAFs [cytosol] [Homo sapiens]
(input)[Reaction:209169] Murine PP2A dephosphorylates Ser259 on phosphorylated human RAF1 [Homo sapiens]
[Reaction:209326] Murine 14-3-3zeta dimer binds to phosphorylated human RAF1 [Homo sapiens]
(output)[Reaction:197502] ERK directly phosphorylates RAF, providing positive feedback [Homo sapiens]
[Reaction:209343] Human PKA phosphorylates RAF1 in the vicinity of its C1 domain [Homo sapiens]
(updatedInstance)[_UpdateTracker:9868569] Update Tracker - [EntityWithAccessionedSequence:109786] p-S259,S621-RAF1 [cytosol] - v31:[modifyName]
[_UpdateTracker:9879969] Update Tracker - [EntityWithAccessionedSequence:109786] p-S259,S621-RAF1 [cytosol] - v44:[modifyEndCoordinate, modifyName]
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No pathways have been reviewed or authored by p-S259,S621-RAF1 [cytosol] (109786)