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Details on Person TFIIH [nucleoplasm]
Class:Id Complex:109634
_displayName TFIIH [nucleoplasm]
_timestamp 2015-04-17 14:25:50
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:109625] Joshi-Tope, G, 2004-01-19 02:18:00
hasComponent
literatureReference [LiteratureReference:5688436] Molecular structure of human TFIIH [LiteratureReference:5688434] Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH [LiteratureReference:5688454] A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A
modified [InstanceEdit:109692] Joshi-Tope, G, 2004-01-19 22:47:00 [InstanceEdit:109874] Joshi-Tope, G, 2004-01-21 14:30:42 [InstanceEdit:109937] Gopinathrao, G, 2004-01-22 20:43:32 [InstanceEdit:110064] Joshi-Tope, G, 2004-01-24 23:40:32 [InstanceEdit:110067] Joshi-Tope, G, 2004-01-27 08:10:00 [InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32 [InstanceEdit:110546] Gopinathrao, G, 2004-02-02 17:30:34 [InstanceEdit:110751] Joshi-Tope, G, 2004-02-06 00:05:56 [InstanceEdit:110753] Joshi-Tope, G, 2004-02-06 11:32:29 [InstanceEdit:111172] Joshi-Tope, G, 2004-02-09 11:58:07 [InstanceEdit:111259] Joshi-Tope, G, 2004-02-11 09:36:36 [InstanceEdit:111441] Joshi-Tope, G, 2004-02-17 20:03:04 [InstanceEdit:111547] Joshi-Tope, G, 2004-02-22 02:29:13 [InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06 [InstanceEdit:5688444] Orlic-Milacic, Marija, 2015-04-16 [InstanceEdit:5688459] Orlic-Milacic, Marija, 2015-04-17
name TFIIH
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:364349] R-HSA-109634.1
(hasComponent) [Complex:73716] RNA Polymerase I transcription initiation complex:45S pre-rRNA gene [nucleoplasm] [Homo sapiens] [Complex:73717] RNA Polymerase I promoter escape complex:45S pre-rRNA gene [nucleoplasm] [Homo sapiens] [Complex:75859] Pol II Promoter Escape Complex [nucleoplasm] [Homo sapiens] [Complex:75878] pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] [Homo sapiens] [Complex:75881] pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] [Homo sapiens] [Complex:75882] pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] [Homo sapiens] [Complex:75890] pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] [Homo sapiens] [Complex:75902] pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] [Homo sapiens] [Complex:77053] RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] [Homo sapiens] [Complex:77056] RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] [Homo sapiens]
(inferredFrom) [Complex:1115106] TFIIH (name copied from entity in Homo sapiens) [nucleoplasm] [Oryza sativa]
(input) [Reaction:73758] Recruitment of RNA Polymerase I:RRN3 to the 45S pre-rRNA gene [Homo sapiens] [Reaction:109639] Formation of the closed pre-initiation complex [Homo sapiens] [Reaction:112379] Recruitment of elongation factors to form elongation complex [Homo sapiens] [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens] [Reaction:167072] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens] [Reaction:167077] Recruitment of elongation factors to form HIV-1 elongation complex [Homo sapiens] [Reaction:167135] Formation of the HIV-1 closed pre-initiation complex [Homo sapiens] [Reaction:167196] Recruitment of elongation factors to form HIV-1 elongation complex [Homo sapiens] [Reaction:5691000] TFIIH binds GG-NER site to form a verification complex [Homo sapiens] [BlackBoxEvent:6781818] RNA Pol II initiates transcription from damaged DNA template [Homo sapiens]
(output) [Reaction:73946] Abortive initiation after formation of the first phosphodiester bond [Homo sapiens] [Reaction:74992] Dissociation of PTRF:RNA Polymerase I:pre-rRNA complex [Homo sapiens] [Reaction:75856] Abortive Initiation Before Second Transition [Homo sapiens] [Reaction:75891] Abortive Initiation After Second Transition [Homo sapiens] [Reaction:77090] Methylation of GMP-cap by RNA Methyltransferase [Homo sapiens] [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens] [Reaction:112385] Addition of nucleotides leads to transcript elongation [Homo sapiens] [Reaction:167072] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens] [Reaction:167181] Addition of nucleotides leads to HIV-1 transcript elongation [Homo sapiens] [Reaction:167395] Methylation of GMP-cap by RNA Methyltransferase [Homo sapiens]
(physicalEntity) [CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
(updatedInstance) [_UpdateTracker:9892228] Update Tracker - [Complex:109634] TFIIH [nucleoplasm] - v53:[addHasComponent, addLiteratureReference]
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Protein identifiers
No pathways have been reviewed or authored by TFIIH [nucleoplasm] (109634)